T-lymphocyte-specific knockout of IKK-2 or NEMO induces Th17 cells in an experimental nephrotoxic nephritis mouse model.
Guo L, Huang J, Chen M, Piotrowski E, Song N, Zahner G, Paust HJ, Alawi M, Geffers R, Thaiss F.
Guo L, et al. Among authors: huang j.
FASEB J. 2019 Feb;33(2):2359-2371. doi: 10.1096/fj.201800485RR. Epub 2018 Oct 4.
FASEB J. 2019.
PMID: 30285578
We propose that better understanding of the role of IKK-2 and NEMO in nephritis is essential for the clinical application of kinase inhibitors in patients with glomerulonephritis.-Guo, L., Huang, J., Chen, M., Piotrowski, E., Song, N., Zahner, G., Paust, H.-J …
We propose that better understanding of the role of IKK-2 and NEMO in nephritis is essential for the clinical application of kinase inhibito …