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Durable SARS-CoV-2 B cell immunity after mild or severe disease.
Ogega CO, Skinner NE, Blair PW, Park HS, Littlefield K, Ganesan A, Dhakal S, Ladiwala P, Antar AA, Ray SC, Betenbaugh MJ, Pekosz A, Klein SL, Manabe YC, Cox AL, Bailey JR. Ogega CO, et al. Among authors: littlefield k. J Clin Invest. 2021 Apr 1;131(7):e145516. doi: 10.1172/JCI145516. J Clin Invest. 2021. PMID: 33571162 Free PMC article.
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population.
Klein SL, Pekosz A, Park HS, Ursin RL, Shapiro JR, Benner SE, Littlefield K, Kumar S, Naik HM, Betenbaugh MJ, Shrestha R, Wu AA, Hughes RM, Burgess I, Caturegli P, Laeyendecker O, Quinn TC, Sullivan D, Shoham S, Redd AD, Bloch EM, Casadevall A, Tobian AA. Klein SL, et al. Among authors: littlefield k. J Clin Invest. 2020 Nov 2;130(11):6141-6150. doi: 10.1172/JCI142004. J Clin Invest. 2020. PMID: 32764200 Free PMC article.
Durable SARS-CoV-2 B cell immunity after mild or severe disease.
Ogega CO, Skinner NE, Blair PW, Park HS, Littlefield K, Ganesan A, Ladiwala P, Antar AA, Ray SC, Betenbaugh MJ, Pekosz A, Klein SL, Manabe YC, Cox AL, Bailey JR. Ogega CO, et al. Among authors: littlefield k. medRxiv [Preprint]. 2020 Oct 30:2020.10.28.20220996. doi: 10.1101/2020.10.28.20220996. medRxiv. 2020. Update in: J Clin Invest. 2021 Apr 1;131(7):145516. doi: 10.1172/JCI145516 PMID: 33140070 Free PMC article. Updated. Preprint.
SARS-CoV-2-specific CD8+ T cell responses in convalescent COVID-19 individuals.
Kared H, Redd AD, Bloch EM, Bonny TS, Sumatoh H, Kairi F, Carbajo D, Abel B, Newell EW, Bettinotti MP, Benner SE, Patel EU, Littlefield K, Laeyendecker O, Shoham S, Sullivan D, Casadevall A, Pekosz A, Nardin A, Fehlings M, Tobian AA, Quinn TC. Kared H, et al. Among authors: littlefield k. J Clin Invest. 2021 Mar 1;131(5):e145476. doi: 10.1172/JCI145476. J Clin Invest. 2021. PMID: 33427749 Free PMC article. Clinical Trial.
Pregnancy alters interleukin-1 beta expression and antiviral antibody responses during severe acute respiratory syndrome coronavirus 2 infection.
Sherer ML, Lei J, Creisher PS, Jang M, Reddy R, Voegtline K, Olson S, Littlefield K, Park HS, Ursin RL, Ganesan A, Boyer T, Elsayed N, Brown DM, Walch SN, Antar AAR, Manabe YC, Jones-Beatty K, Golden WC, Satin AJ, Sheffield JS, Pekosz A, Klein SL, Burd I. Sherer ML, et al. Among authors: littlefield k. Am J Obstet Gynecol. 2021 Sep;225(3):301.e1-301.e14. doi: 10.1016/j.ajog.2021.03.028. Epub 2021 Mar 30. Am J Obstet Gynecol. 2021. PMID: 33798476 Free PMC article.
Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model.
Dhakal S, Ruiz-Bedoya CA, Zhou R, Creisher PS, Villano JS, Littlefield K, Ruelas Castillo J, Marinho P, Jedlicka AE, Ordonez AA, Bahr M, Majewska N, Betenbaugh MJ, Flavahan K, Mueller ARL, Looney MM, Quijada D, Mota F, Beck SE, Brockhurst J, Braxton AM, Castell N, Stover M, D'Alessio FR, Metcalf Pate KA, Karakousis PC, Mankowski JL, Pekosz A, Jain SK, Klein SL; Johns Hopkins COVID-19 Hamster Study Group. Dhakal S, et al. Among authors: littlefield k. mBio. 2021 Aug 31;12(4):e0097421. doi: 10.1128/mBio.00974-21. Epub 2021 Jul 13. mBio. 2021. PMID: 34253053 Free PMC article.
Progression and Resolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Golden Syrian Hamsters.
Mulka KR, Beck SE, Solis CV, Johanson AL, Queen SE, McCarron ME, Richardson MR, Zhou R, Marinho P, Jedlicka A, Guerrero-Martin S, Shirk EN, Braxton AM, Brockhurst J, Creisher PS, Dhakal S, Brayton CF, Veenhuis RT, Metcalf Pate KA, Karakousis PC, Zahnow CA, Klein SL, Jain SK, Tarwater PM, Pekosz AS, Villano JS, Mankowski JL; Johns Hopkins COVID-19 Hamster Study Group. Mulka KR, et al. Am J Pathol. 2022 Feb;192(2):195-207. doi: 10.1016/j.ajpath.2021.10.009. Epub 2021 Nov 10. Am J Pathol. 2022. PMID: 34767812 Free PMC article.
SARS-CoV-2 Antibody Avidity Responses in COVID-19 Patients and Convalescent Plasma Donors.
Benner SE, Patel EU, Laeyendecker O, Pekosz A, Littlefield K, Eby Y, Fernandez RE, Miller J, Kirby CS, Keruly M, Klock E, Baker OR, Schmidt HA, Shrestha R, Burgess I, Bonny TS, Clarke W, Caturegli P, Sullivan D, Shoham S, Quinn TC, Bloch EM, Casadevall A, Tobian AAR, Redd AD. Benner SE, et al. Among authors: littlefield k. J Infect Dis. 2020 Nov 13;222(12):1974-1984. doi: 10.1093/infdis/jiaa581. J Infect Dis. 2020. PMID: 32910175 Free PMC article.
Comparative Performance of Five Commercially Available Serologic Assays To Detect Antibodies to SARS-CoV-2 and Identify Individuals with High Neutralizing Titers.
Patel EU, Bloch EM, Clarke W, Hsieh YH, Boon D, Eby Y, Fernandez RE, Baker OR, Keruly M, Kirby CS, Klock E, Littlefield K, Miller J, Schmidt HA, Sullivan P, Piwowar-Manning E, Shrestha R, Redd AD, Rothman RE, Sullivan D, Shoham S, Casadevall A, Quinn TC, Pekosz A, Tobian AAR, Laeyendecker O. Patel EU, et al. Among authors: littlefield k. J Clin Microbiol. 2021 Jan 21;59(2):e02257-20. doi: 10.1128/JCM.02257-20. Print 2021 Jan 21. J Clin Microbiol. 2021. PMID: 33139419 Free PMC article.
Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality.
Morgenlander WR, Henson SN, Monaco DR, Chen A, Littlefield K, Bloch EM, Fujimura E, Ruczinski I, Crowley AR, Natarajan H, Butler SE, Weiner JA, Li MZ, Bonny TS, Benner SE, Balagopal A, Sullivan D, Shoham S, Quinn TC, Eshleman SH, Casadevall A, Redd AD, Laeyendecker O, Ackerman ME, Pekosz A, Elledge SJ, Robinson M, Tobian AA, Larman HB. Morgenlander WR, et al. Among authors: littlefield k. J Clin Invest. 2021 Apr 1;131(7):e146927. doi: 10.1172/JCI146927. J Clin Invest. 2021. PMID: 33571169 Free PMC article.
62 results