Newsom S - Search Results

1

The CRISPR-Cas Mechanism for Adaptive Immunity and Alternate Bacterial Functions Fuels Diverse Biotechnologies.

Newsom S, Parameshwaran HP, Martin L, Rajan R. Newsom S, et al. Front Cell Infect Microbiol. 2021 Jan 28;10:619763. doi: 10.3389/fcimb.2020.619763. eCollection 2020. Front Cell Infect Microbiol. 2021. PMID: 33585286 Free PMC article. Review.

2

CRISPR type II-A subgroups exhibit phylogenetically distinct mechanisms for prespacer insertion.

Van Orden MJ, Newsom S, Rajan R. Van Orden MJ, et al. Among authors: newsom s. J Biol Chem. 2020 Aug 7;295(32):10956-10968. doi: 10.1074/jbc.RA120.013554. Epub 2020 Jun 8. J Biol Chem. 2020. PMID: 32513871 Free PMC article.

3

Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence.

Babu K, Kathiresan V, Kumari P, Newsom S, Parameshwaran HP, Chen X, Liu J, Qin PZ, Rajan R. Babu K, et al. Among authors: newsom s. Biochemistry. 2021 Dec 14;60(49):3783-3800. doi: 10.1021/acs.biochem.1c00354. Epub 2021 Nov 10. Biochemistry. 2021. PMID: 34757726 Free PMC article.

4

Rational Engineering of CRISPR-Cas9 Nuclease to Attenuate Position-Dependent Off-Target Effects.

Zuo Z, Babu K, Ganguly C, Zolekar A, Newsom S, Rajan R, Wang YC, Liu J. Zuo Z, et al. Among authors: newsom s. CRISPR J. 2022 Apr;5(2):329-340. doi: 10.1089/crispr.2021.0076. CRISPR J. 2022. PMID: 35438515 Free PMC article.

5

Differential Divalent Metal Binding by SpyCas9's RuvC Active Site Contributes to Nonspecific DNA Cleavage.

Newsom SN, Wang DS, Rostami S, Schuster I, Parameshwaran HP, Joseph YG, Qin PZ, Liu J, Rajan R. Newsom SN, et al. CRISPR J. 2023 Dec;6(6):527-542. doi: 10.1089/crispr.2023.0022. CRISPR J. 2023. PMID: 38108519 Free PMC article.

6

Metabolomics: Eavesdropping on silent conversations between hosts and their unwelcome guests.

Newsom SN, McCall LI. Newsom SN, et al. PLoS Pathog. 2018 Apr 5;14(4):e1006926. doi: 10.1371/journal.ppat.1006926. eCollection 2018 Apr. PLoS Pathog. 2018. PMID: 29621358 Free PMC article. No abstract available.

7

Combined diet and exercise training decreases serum lipids associated with insulin resistance.

Broussard JL, Garfield A, Zarini S, Brozinick JT, Perreault L, Newsom SA, Kahn D, Kerege A, Berry KZ, Bui HH, Bergman BC. Broussard JL, et al. Among authors: newsom sa. Obesity (Silver Spring). 2024 Dec;32(12):2334-2344. doi: 10.1002/oby.24156. Obesity (Silver Spring). 2024. PMID: 39587896

8

Intramuscular diacylglycerol accumulates with acute hyperinsulinemia in insulin-resistant phenotypes.

McKenna CF, Stierwalt HD, Zemski Berry KA, Ehrlicher SE, Robinson MM, Zarini S, Kahn DE, Snell-Bergeon JK, Perreault L, Bergman BC, Newsom SA. McKenna CF, et al. Among authors: newsom sa. Am J Physiol Endocrinol Metab. 2024 Aug 1;327(2):E183-E193. doi: 10.1152/ajpendo.00368.2023. Epub 2024 Jun 19. Am J Physiol Endocrinol Metab. 2024. PMID: 38895980

9

Recent advances in understanding the mechanisms in skeletal muscle of interaction between exercise and frontline antihyperglycemic drugs.

Newsom SA, Robinson MM. Newsom SA, et al. Physiol Rep. 2024 Jun;12(11):e16093. doi: 10.14814/phy2.16093. Physiol Rep. 2024. PMID: 38845596 Free PMC article. Review.

10

IdMotif: An Interactive Motif Identification in Protein Sequences.

Park JH, Prasad V, Newsom S, Najar F, Rajan R. Park JH, et al. Among authors: newsom s. IEEE Comput Graph Appl. 2024 May-Jun;44(3):114-125. doi: 10.1109/MCG.2023.3345742. Epub 2024 Jun 21. IEEE Comput Graph Appl. 2024. PMID: 38127603

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