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Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses.
Lo JA, Kawakubo M, Juneja VR, Su MY, Erlich TH, LaFleur MW, Kemeny LV, Rashid M, Malehmir M, Rabi SA, Raghavan R, Allouche J, Kasumova G, Frederick DT, Pauken KE, Weng QY, Pereira da Silva M, Xu Y, van der Sande AAJ, Silkworth W, Roider E, Browne EP, Lieb DJ, Wang B, Garraway LA, Wu CJ, Flaherty KT, Brinckerhoff CE, Mullins DW, Adams DJ, Hacohen N, Hoang MP, Boland GM, Freeman GJ, Sharpe AH, Manstein D, Fisher DE. Lo JA, et al. Among authors: wu cj. Sci Transl Med. 2021 Feb 17;13(581):eabd8636. doi: 10.1126/scitranslmed.abd8636. Sci Transl Med. 2021. PMID: 33597266 Free PMC article.
Reversal of in situ T-cell exhaustion during effective human antileukemia responses to donor lymphocyte infusion.
Bachireddy P, Hainz U, Rooney M, Pozdnyakova O, Aldridge J, Zhang W, Liao X, Hodi FS, O'Connell K, Haining WN, Goldstein NR, Canning CM, Soiffer RJ, Ritz J, Hacohen N, Alyea EP 3rd, Kim HT, Wu CJ. Bachireddy P, et al. Among authors: wu cj. Blood. 2014 Feb 27;123(9):1412-21. doi: 10.1182/blood-2013-08-523001. Epub 2013 Dec 19. Blood. 2014. PMID: 24357730 Free PMC article.
Getting personal with neoantigen-based therapeutic cancer vaccines.
Hacohen N, Fritsch EF, Carter TA, Lander ES, Wu CJ. Hacohen N, et al. Among authors: wu cj. Cancer Immunol Res. 2013 Jul;1(1):11-5. doi: 10.1158/2326-6066.CIR-13-0022. Epub 2013 Apr 7. Cancer Immunol Res. 2013. PMID: 24777245 Free PMC article.
Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia.
Rajasagi M, Shukla SA, Fritsch EF, Keskin DB, DeLuca D, Carmona E, Zhang W, Sougnez C, Cibulskis K, Sidney J, Stevenson K, Ritz J, Neuberg D, Brusic V, Gabriel S, Lander ES, Getz G, Hacohen N, Wu CJ. Rajasagi M, et al. Among authors: wu cj. Blood. 2014 Jul 17;124(3):453-62. doi: 10.1182/blood-2014-04-567933. Epub 2014 Jun 2. Blood. 2014. PMID: 24891321 Free PMC article.
HLA-binding properties of tumor neoepitopes in humans.
Fritsch EF, Rajasagi M, Ott PA, Brusic V, Hacohen N, Wu CJ. Fritsch EF, et al. Among authors: wu cj. Cancer Immunol Res. 2014 Jun;2(6):522-9. doi: 10.1158/2326-6066.CIR-13-0227. Epub 2014 Mar 3. Cancer Immunol Res. 2014. PMID: 24894089 Free PMC article. Review.
Personal neoantigen cancer vaccines: The momentum builds.
Fritsch EF, Hacohen N, Wu CJ. Fritsch EF, et al. Among authors: wu cj. Oncoimmunology. 2014 Jun 25;3:e29311. doi: 10.4161/onci.29311. eCollection 2014. Oncoimmunology. 2014. PMID: 25101225 Free PMC article.
Immunotherapy advances for glioblastoma.
Reardon DA, Freeman G, Wu C, Chiocca EA, Wucherpfennig KW, Wen PY, Fritsch EF, Curry WT Jr, Sampson JH, Dranoff G. Reardon DA, et al. Neuro Oncol. 2014 Nov;16(11):1441-58. doi: 10.1093/neuonc/nou212. Epub 2014 Sep 4. Neuro Oncol. 2014. PMID: 25190673 Free PMC article. Review.
Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.
Landau DA, Clement K, Ziller MJ, Boyle P, Fan J, Gu H, Stevenson K, Sougnez C, Wang L, Li S, Kotliar D, Zhang W, Ghandi M, Garraway L, Fernandes SM, Livak KJ, Gabriel S, Gnirke A, Lander ES, Brown JR, Neuberg D, Kharchenko PV, Hacohen N, Getz G, Meissner A, Wu CJ. Landau DA, et al. Among authors: wu cj. Cancer Cell. 2014 Dec 8;26(6):813-825. doi: 10.1016/j.ccell.2014.10.012. Cancer Cell. 2014. PMID: 25490447 Free PMC article.
1,898 results