Hilton JK - Search Results

1

Structure and inhibition mechanism of the human citrate transporter NaCT.

Sauer DB, Song J, Wang B, Hilton JK, Karpowich NK, Mindell JA, Rice WJ, Wang DN. Sauer DB, et al. Among authors: hilton jk. Nature. 2021 Mar;591(7848):157-161. doi: 10.1038/s41586-021-03230-x. Epub 2021 Feb 17. Nature. 2021. PMID: 33597751 Free PMC article.

2

Tonic inhibition of the chloride/proton antiporter ClC-7 by PI(3,5)P2 is crucial for lysosomal pH maintenance.

Leray X, Hilton JK, Nwangwu K, Becerril A, Mikusevic V, Fitzgerald G, Amin A, Weston MR, Mindell JA. Leray X, et al. Among authors: hilton jk. Elife. 2022 Jun 7;11:e74136. doi: 10.7554/eLife.74136. Elife. 2022. PMID: 35670560 Free PMC article.

3

New pieces to an old puzzle: identifying the warfarin-binding site that prevents clotting.

Hilton JK, Van Horn WD. Hilton JK, et al. Nat Struct Mol Biol. 2017 Jan 5;24(1):5-6. doi: 10.1038/nsmb.3356. Nat Struct Mol Biol. 2017. PMID: 28054569 No abstract available.

4

Evidence that the TRPV1 S1-S4 membrane domain contributes to thermosensing.

Kim M, Sisco NJ, Hilton JK, Montano CM, Castro MA, Cherry BR, Levitus M, Van Horn WD. Kim M, et al. Among authors: hilton jk. Nat Commun. 2020 Aug 20;11(1):4169. doi: 10.1038/s41467-020-18026-2. Nat Commun. 2020. PMID: 32820172 Free PMC article.

5

Understanding thermosensitive transient receptor potential channels as versatile polymodal cellular sensors.

Hilton JK, Rath P, Helsell CV, Beckstein O, Van Horn WD. Hilton JK, et al. Biochemistry. 2015 Apr 21;54(15):2401-13. doi: 10.1021/acs.biochem.5b00071. Epub 2015 Apr 3. Biochemistry. 2015. PMID: 25812016 Review.

6

Implications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing Domain.

Rath P, Hilton JK, Sisco NJ, Van Horn WD. Rath P, et al. Among authors: hilton jk. Biochemistry. 2016 Jan 12;55(1):114-24. doi: 10.1021/acs.biochem.5b00931. Epub 2015 Dec 23. Biochemistry. 2016. PMID: 26653082 Free PMC article.

7

Phosphoinositide-interacting regulator of TRP (PIRT) has opposing effects on human and mouse TRPM8 ion channels.

Hilton JK, Salehpour T, Sisco NJ, Rath P, Van Horn WD. Hilton JK, et al. J Biol Chem. 2018 Jun 15;293(24):9423-9434. doi: 10.1074/jbc.RA118.003563. Epub 2018 May 3. J Biol Chem. 2018. PMID: 29724821 Free PMC article.

8

Structural and Evolutionary Insights Point to Allosteric Regulation of TRP Ion Channels.

Hilton JK, Kim M, Van Horn WD. Hilton JK, et al. Acc Chem Res. 2019 Jun 18;52(6):1643-1652. doi: 10.1021/acs.accounts.9b00075. Epub 2019 May 31. Acc Chem Res. 2019. PMID: 31149807 Free PMC article.

9

Structure-Based Design of Novel Biphenyl Amide Antagonists of Human Transient Receptor Potential Cation Channel Subfamily M Member 8 Channels with Potential Implications in the Treatment of Sensory Neuropathies.

Journigan VB, Feng Z, Rahman S, Wang Y, Amin ARMR, Heffner CE, Bachtel N, Wang S, Gonzalez-Rodriguez S, Fernández-Carvajal A, Fernández-Ballester G, Hilton JK, Van Horn WD, Ferrer-Montiel A, Xie XQ, Rahman T. Journigan VB, et al. Among authors: hilton jk. ACS Chem Neurosci. 2020 Feb 5;11(3):268-290. doi: 10.1021/acschemneuro.9b00404. Epub 2020 Jan 9. ACS Chem Neurosci. 2020. PMID: 31850745 Free PMC article.

10

Woman in Dentistry.

Hilton JK. Hilton JK. Dent Regist. 1887 Nov;41(11):525-528. Dent Regist. 1887. PMID: 33703050 Free PMC article. No abstract available.

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