Mindell JA - Search Results

1

Structure and inhibition mechanism of the human citrate transporter NaCT.

Sauer DB, Song J, Wang B, Hilton JK, Karpowich NK, Mindell JA, Rice WJ, Wang DN. Sauer DB, et al. Among authors: mindell ja. Nature. 2021 Mar;591(7848):157-161. doi: 10.1038/s41586-021-03230-x. Epub 2021 Feb 17. Nature. 2021. PMID: 33597751 Free PMC article.

2

Functional characterization of a Na+-dependent dicarboxylate transporter from Vibrio cholerae.

Mulligan C, Fitzgerald GA, Wang DN, Mindell JA. Mulligan C, et al. Among authors: mindell ja. J Gen Physiol. 2014 Jun;143(6):745-59. doi: 10.1085/jgp.201311141. Epub 2014 May 12. J Gen Physiol. 2014. PMID: 24821967 Free PMC article.

3

The bacterial dicarboxylate transporter VcINDY uses a two-domain elevator-type mechanism.

Mulligan C, Fenollar-Ferrer C, Fitzgerald GA, Vergara-Jaque A, Kaufmann D, Li Y, Forrest LR, Mindell JA. Mulligan C, et al. Among authors: mindell ja. Nat Struct Mol Biol. 2016 Mar;23(3):256-63. doi: 10.1038/nsmb.3166. Epub 2016 Feb 1. Nat Struct Mol Biol. 2016. PMID: 26828963 Free PMC article.

4

Solvent accessibility changes in a Na⁺-dependent C₄-dicarboxylate transporter suggest differential substrate effects in a multistep mechanism.

Sampson CDD, Stewart MJ, Mindell JA, Mulligan C. Sampson CDD, et al. Among authors: mindell ja. J Biol Chem. 2020 Dec 25;295(52):18524-18538. doi: 10.1074/jbc.RA120.013894. Epub 2020 Oct 21. J Biol Chem. 2020. PMID: 33087444 Free PMC article.

5

Tonic inhibition of the chloride/proton antiporter ClC-7 by PI(3,5)P2 is crucial for lysosomal pH maintenance.

Leray X, Hilton JK, Nwangwu K, Becerril A, Mikusevic V, Fitzgerald G, Amin A, Weston MR, Mindell JA. Leray X, et al. Among authors: mindell ja. Elife. 2022 Jun 7;11:e74136. doi: 10.7554/eLife.74136. Elife. 2022. PMID: 35670560 Free PMC article.

6

Substrate translocation and inhibition in human dicarboxylate transporter NaDC3.

Li Y, Song J, Mikusevic V, Marden JJ, Becerril A, Kuang H, Wang B, Rice WJ, Mindell JA, Wang DN. Li Y, et al. Among authors: mindell ja. Nat Struct Mol Biol. 2024 Dec 2. doi: 10.1038/s41594-024-01433-0. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 39622972

7

Voltage-sensor activation with a tarantula toxin as cargo.

Phillips LR, Milescu M, Li-Smerin Y, Mindell JA, Kim JI, Swartz KJ. Phillips LR, et al. Among authors: mindell ja. Nature. 2005 Aug 11;436(7052):857-60. doi: 10.1038/nature03873. Nature. 2005. PMID: 16094370

8

The uncoupled chloride conductance of a bacterial glutamate transporter homolog.

Ryan RM, Mindell JA. Ryan RM, et al. Among authors: mindell ja. Nat Struct Mol Biol. 2007 May;14(5):365-71. doi: 10.1038/nsmb1230. Epub 2007 Apr 15. Nat Struct Mol Biol. 2007. PMID: 17435767

9

The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes.

Graves AR, Curran PK, Smith CL, Mindell JA. Graves AR, et al. Among authors: mindell ja. Nature. 2008 Jun 5;453(7196):788-92. doi: 10.1038/nature06907. Epub 2008 Apr 30. Nature. 2008. PMID: 18449189

10

The 3-4 loop of an archaeal glutamate transporter homolog experiences ligand-induced structural changes and is essential for transport.

Compton EL, Taylor EM, Mindell JA. Compton EL, et al. Among authors: mindell ja. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):12840-5. doi: 10.1073/pnas.1003046107. Epub 2010 Jul 6. Proc Natl Acad Sci U S A. 2010. PMID: 20615993 Free PMC article.

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