Thomas D - Search Results

1

Epigenetic regulation of cardiac electrophysiology in atrial fibrillation: HDAC2 determines action potential duration and suppresses NRSF in cardiomyocytes.

Lugenbiel P, Govorov K, Syren P, Rahm AK, Wieder T, Wunsch M, Weiberg N, Manolova E, Gramlich D, Rivinius R, Finke D, Lehmann LH, Schweizer PA, Frank D, El Tahry FA, Bruehl C, Heimberger T, Sandke S, Weis T, Most P, Schmack B, Ruhparwar A, Karck M, Frey N, Katus HA, Thomas D. Lugenbiel P, et al. Among authors: thomas d. Basic Res Cardiol. 2021 Feb 25;116(1):13. doi: 10.1007/s00395-021-00855-x. Basic Res Cardiol. 2021. PMID: 33630168

2

Human cardiac inwardly-rectifying K+ channel Kir(2.1b) is inhibited by direct protein kinase C-dependent regulation in human isolated cardiomyocytes and in an expression system.

Karle CA, Zitron E, Zhang W, Wendt-Nordahl G, Kathöfer S, Thomas D, Gut B, Scholz E, Vahl CF, Katus HA, Kiehn J. Karle CA, et al. Among authors: thomas d. Circulation. 2002 Sep 17;106(12):1493-9. doi: 10.1161/01.cir.0000029747.53262.5c. Circulation. 2002. PMID: 12234954

3

The antipsychotic drug chlorpromazine inhibits HERG potassium channels.

Thomas D, Wu K, Kathöfer S, Katus HA, Schoels W, Kiehn J, Karle CA. Thomas D, et al. Br J Pharmacol. 2003 Jun;139(3):567-74. doi: 10.1038/sj.bjp.0705283. Br J Pharmacol. 2003. PMID: 12788816 Free PMC article.

4

Inhibition of cloned HERG potassium channels by the antiestrogen tamoxifen.

Thomas D, Gut B, Karsai S, Wimmer AB, Wu K, Wendt-Nordahl G, Zhang W, Kathöfer S, Schoels W, Katus HA, Kiehn J, Karle CA. Thomas D, et al. Naunyn Schmiedebergs Arch Pharmacol. 2003 Jul;368(1):41-8. doi: 10.1007/s00210-003-0766-8. Epub 2003 Jun 25. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 12827215

5

Regulation of HERG potassium channel activation by protein kinase C independent of direct phosphorylation of the channel protein.

Thomas D, Zhang W, Wu K, Wimmer AB, Gut B, Wendt-Nordahl G, Kathöfer S, Kreye VA, Katus HA, Schoels W, Kiehn J, Karle CA. Thomas D, et al. Cardiovasc Res. 2003 Jul 1;59(1):14-26. doi: 10.1016/s0008-6363(03)00386-9. Cardiovasc Res. 2003. PMID: 12829172

6

Human beta(3)-adrenoreceptors couple to KvLQT1/MinK potassium channels in Xenopus oocytes via protein kinase C phosphorylation of the KvLQT1 protein.

Kathöfer S, Röckl K, Zhang W, Thomas D, Katus H, Kiehn J, Kreye V, Schoels W, Karle C. Kathöfer S, et al. Among authors: thomas d. Naunyn Schmiedebergs Arch Pharmacol. 2003 Aug;368(2):119-26. doi: 10.1007/s00210-003-0772-x. Epub 2003 Jul 19. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 12879210

7

Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels.

Thomas D, Kathofer S, Zhang W, Wu K, Wimmer AB, Zitron E, Kreye VA, Katus HA, Schoels W, Karle CA, Kiehn J. Thomas D, et al. Br J Pharmacol. 2003 Nov;140(5):996-1002. doi: 10.1038/sj.bjp.0705502. Epub 2003 Sep 29. Br J Pharmacol. 2003. PMID: 14517175 Free PMC article.

8

Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine.

Scholz EP, Zitron E, Kiesecker C, Lueck S, Kathöfer S, Thomas D, Weretka S, Peth S, Kreye VA, Schoels W, Katus HA, Kiehn J, Karle CA. Scholz EP, et al. Among authors: thomas d. Naunyn Schmiedebergs Arch Pharmacol. 2003 Nov;368(5):404-14. doi: 10.1007/s00210-003-0805-5. Epub 2003 Oct 14. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 14557918

9

Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): molecular mechanisms and restoration of intracellular protein processing.

Thomas D, Kiehn J, Katus HA, Karle CA. Thomas D, et al. Cardiovasc Res. 2003 Nov 1;60(2):235-41. doi: 10.1016/j.cardiores.2003.08.002. Cardiovasc Res. 2003. PMID: 14613852 Review.

10

Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin.

Thomas D, Wimmer AB, Wu K, Hammerling BC, Ficker EK, Kuryshev YA, Kiehn J, Katus HA, Schoels W, Karle CA. Thomas D, et al. Naunyn Schmiedebergs Arch Pharmacol. 2004 May;369(5):462-72. doi: 10.1007/s00210-004-0931-8. Epub 2004 Apr 20. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 15098086

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