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Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells.
Weng MT, Lee JH, Wei SC, Li Q, Shahamatdar S, Hsu D, Schetter AJ, Swatkoski S, Mannan P, Garfield S, Gucek M, Kim MK, Annunziata CM, Creighton CJ, Emanuele MJ, Harris CC, Sheu JC, Giaccone G, Luo J. Weng MT, et al. Among authors: luo j. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):E3659-67. doi: 10.1073/pnas.1207673110. Epub 2012 Dec 10. Proc Natl Acad Sci U S A. 2012. PMID: 23236152 Free PMC article.
Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9.
Yu B, Swatkoski S, Holly A, Lee LC, Giroux V, Lee CS, Hsu D, Smith JL, Yuen G, Yue J, Ann DK, Simpson RM, Creighton CJ, Figg WD, Gucek M, Luo J. Yu B, et al. Among authors: luo j. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1724-33. doi: 10.1073/pnas.1415569112. Epub 2015 Mar 24. Proc Natl Acad Sci U S A. 2015. PMID: 25805818 Free PMC article.
SUMO wrestling with Ras.
Zhang H, Luo J. Zhang H, et al. Among authors: luo j. Small GTPases. 2016 Apr 2;7(2):39-46. doi: 10.1080/21541248.2016.1161698. Epub 2016 Apr 8. Small GTPases. 2016. PMID: 27057691 Free PMC article. Review.
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