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Review article: The need for more efficient and patient-oriented drug development pathways in NASH-setting the scene for platform trials.
Pericàs JM, Di Prospero NA, Anstee QM, Mesenbrinck P, Kjaer MS, Rivera-Esteban J, Koenig F, Sena E, Pais R, Manzano R, Genescà J, Tacke F, Ratziu V; EU-PEARL NASH Investigators. Pericàs JM, et al. Aliment Pharmacol Ther. 2023 May;57(9):948-961. doi: 10.1111/apt.17456. Epub 2023 Mar 14. Aliment Pharmacol Ther. 2023. PMID: 36918740 Review.
Regulatory Issues of Platform Trials: Learnings from EU-PEARL.
Nguyen QL, Hees K, Hernandez Penna S, König F, Posch M, Bofill Roig M, Meyer EL, Freitag MM, Parke T, Otte M, Dauben HP, Mielke T, Spiertz C, Mesenbrink P, Gidh-Jain M, Pierre S, Morello S, Hofner B. Nguyen QL, et al. Among authors: mielke t. Clin Pharmacol Ther. 2024 Jul;116(1):52-63. doi: 10.1002/cpt.3244. Epub 2024 Mar 26. Clin Pharmacol Ther. 2024. PMID: 38529786 Review.
Why and how should we simulate platform trials? Learnings from EU-PEARL.
Meyer EL, Mielke T, Bofill Roig M, Freitag MM, Jacko P, Krotka P, Mesenbrink P, Parke T, Zehetmayer S, Zocholl D, König F. Meyer EL, et al. Among authors: mielke t. BMC Med Res Methodol. 2025 Jan 17;25(1):12. doi: 10.1186/s12874-024-02453-6. BMC Med Res Methodol. 2025. PMID: 39819305 Free PMC article.
Blobby is a synaptic active zone assembly protein required for memory in Drosophila.
Lützkendorf J, Matkovic-Rachid T, Liu S, Götz T, Gao L, Turrel O, Maglione M, Grieger M, Putignano S, Ramesh N, Ghelani T, Neumann A, Gimber N, Schmoranzer J, Stawrakakis A, Brence B, Baum D, Ludwig K, Heine M, Mielke T, Liu F, Walter AM, Wahl MC, Sigrist SJ. Lützkendorf J, et al. Among authors: mielke t. Nat Commun. 2025 Jan 2;16(1):271. doi: 10.1038/s41467-024-55382-9. Nat Commun. 2025. PMID: 39747038 Free PMC article.
Bimodal intensity-modulated radiotherapy in combination with carbon ion therapy (C12) of mucosal melanomas - data of the last decade from Heidelberg University Hospital.
Bauer L, Paul A, Regnery S, Deng MY, Ellerbrock M, Mielke T, Harrabi SB, Seidensaal K, Held T, Herfarth K, Debus J, Hassel JC, Uzun-Lang K. Bauer L, et al. Among authors: mielke t. Front Oncol. 2024 Nov 22;14:1437412. doi: 10.3389/fonc.2024.1437412. eCollection 2024. Front Oncol. 2024. PMID: 39650062 Free PMC article.
123 results