Lemmon MA - Search Results

1

Computational studies of anaplastic lymphoma kinase mutations reveal common mechanisms of oncogenic activation.

Patil K, Jordan EJ, Park JH, Suresh K, Smith CM, Lemmon AA, Mossé YP, Lemmon MA, Radhakrishnan R. Patil K, et al. Among authors: lemmon aa, lemmon ma. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2019132118. doi: 10.1073/pnas.2019132118. Proc Natl Acad Sci U S A. 2021. PMID: 33674381 Free PMC article.

2

The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function.

Mattoon D, Klein P, Lemmon MA, Lax I, Schlessinger J. Mattoon D, et al. Among authors: lemmon ma. Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):923-8. doi: 10.1073/pnas.0307286101. Epub 2004 Jan 19. Proc Natl Acad Sci U S A. 2004. PMID: 14732693 Free PMC article.

3

A structure-based model for ligand binding and dimerization of EGF receptors.

Klein P, Mattoon D, Lemmon MA, Schlessinger J. Klein P, et al. Among authors: lemmon ma. Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):929-34. doi: 10.1073/pnas.0307285101. Epub 2004 Jan 19. Proc Natl Acad Sci U S A. 2004. PMID: 14732694 Free PMC article.

4

A possible effector role for the pleckstrin homology (PH) domain of dynamin.

Bethoney KA, King MC, Hinshaw JE, Ostap EM, Lemmon MA. Bethoney KA, et al. Among authors: lemmon ma. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13359-64. doi: 10.1073/pnas.0906945106. Epub 2009 Aug 3. Proc Natl Acad Sci U S A. 2009. PMID: 19666604 Free PMC article.

5

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation.

Shi F, Telesco SE, Liu Y, Radhakrishnan R, Lemmon MA. Shi F, et al. Among authors: lemmon ma. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7692-7. doi: 10.1073/pnas.1002753107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351256 Free PMC article.

6

Molecular dynamics analysis of conserved hydrophobic and hydrophilic bond-interaction networks in ErbB family kinases.

Shih AJ, Telesco SE, Choi SH, Lemmon MA, Radhakrishnan R. Shih AJ, et al. Among authors: lemmon ma. Biochem J. 2011 Jun 1;436(2):241-51. doi: 10.1042/BJ20101791. Biochem J. 2011. PMID: 21426301 Free PMC article.

7

Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma.

Bresler SC, Wood AC, Haglund EA, Courtright J, Belcastro LT, Plegaria JS, Cole K, Toporovskaya Y, Zhao H, Carpenter EL, Christensen JG, Maris JM, Lemmon MA, Mossé YP. Bresler SC, et al. Among authors: lemmon ma. Sci Transl Med. 2011 Nov 9;3(108):108ra114. doi: 10.1126/scitranslmed.3002950. Sci Transl Med. 2011. PMID: 22072639 Free PMC article.

8

Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma.

Carpenter EL, Haglund EA, Mace EM, Deng D, Martinez D, Wood AC, Chow AK, Weiser DA, Belcastro LT, Winter C, Bresler SC, Vigny M, Mazot P, Asgharzadeh S, Seeger RC, Zhao H, Guo R, Christensen JG, Orange JS, Pawel BR, Lemmon MA, Mossé YP. Carpenter EL, et al. Among authors: lemmon ma. Oncogene. 2012 Nov 15;31(46):4859-67. doi: 10.1038/onc.2011.647. Epub 2012 Jan 23. Oncogene. 2012. PMID: 22266870 Free PMC article.

9

Occupy EGFR.

Park JH, Lemmon MA. Park JH, et al. Among authors: lemmon ma. Cancer Discov. 2012 May;2(5):398-400. doi: 10.1158/2159-8290.CD-12-0144. Cancer Discov. 2012. PMID: 22588876 Free PMC article.

10

Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain.

Park JH, Liu Y, Lemmon MA, Radhakrishnan R. Park JH, et al. Among authors: lemmon ma. Biochem J. 2012 Dec 15;448(3):417-23. doi: 10.1042/BJ20121513. Biochem J. 2012. PMID: 23101586 Free PMC article.

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