Wang Z - Search Results

1

Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.

Zou L, Zhang X, Xiong M, Meng L, Tian Y, Pan L, Yuan X, Chen G, Wang Z, Bu L, Yao Z, Zhang Z, Ye K, Zhang Z. Zou L, et al. Among authors: wang z. Neurobiol Dis. 2021 Jul;154:105326. doi: 10.1016/j.nbd.2021.105326. Epub 2021 Mar 4. Neurobiol Dis. 2021. PMID: 33677035 Free article.

2

Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial Parkin.

Hu Y, Li XC, Wang ZH, Luo Y, Zhang X, Liu XP, Feng Q, Wang Q, Yue Z, Chen Z, Ye K, Wang JZ, Liu GP. Hu Y, et al. Among authors: wang zh, wang jz, wang q. Oncotarget. 2016 Apr 5;7(14):17356-68. doi: 10.18632/oncotarget.7861. Oncotarget. 2016. PMID: 26943044 Free PMC article.

3

Human wild-type full-length tau accumulation disrupts mitochondrial dynamics and the functions via increasing mitofusins.

Li XC, Hu Y, Wang ZH, Luo Y, Zhang Y, Liu XP, Feng Q, Wang Q, Ye K, Liu GP, Wang JZ. Li XC, et al. Sci Rep. 2016 Apr 21;6:24756. doi: 10.1038/srep24756. Sci Rep. 2016. PMID: 27099072 Free PMC article.

4

Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling.

Yin Y, Gao D, Wang Y, Wang ZH, Wang X, Ye J, Wu D, Fang L, Pi G, Yang Y, Wang XC, Lu C, Ye K, Wang JZ. Yin Y, et al. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3773-81. doi: 10.1073/pnas.1604519113. Epub 2016 Jun 13. Proc Natl Acad Sci U S A. 2016. PMID: 27298345 Free PMC article.

5

Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer's Disease.

Wang ZH, Liu P, Liu X, Manfredsson FP, Sandoval IM, Yu SP, Wang JZ, Ye K. Wang ZH, et al. Mol Cell. 2017 Sep 7;67(5):812-825.e5. doi: 10.1016/j.molcel.2017.07.018. Epub 2017 Aug 17. Mol Cell. 2017. PMID: 28826672 Free PMC article.

6

The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer's disease.

Chen C, Wang Z, Zhang Z, Liu X, Kang SS, Zhang Y, Ye K. Chen C, et al. Among authors: wang z. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):578-583. doi: 10.1073/pnas.1718683115. Epub 2018 Jan 2. Proc Natl Acad Sci U S A. 2018. PMID: 29295929 Free PMC article.

7

C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease.

Wang ZH, Gong K, Liu X, Zhang Z, Sun X, Wei ZZ, Yu SP, Manfredsson FP, Sandoval IM, Johnson PF, Jia J, Wang JZ, Ye K. Wang ZH, et al. Among authors: wang jz. Nat Commun. 2018 May 3;9(1):1784. doi: 10.1038/s41467-018-04120-z. Nat Commun. 2018. PMID: 29725016 Free PMC article.

8

BDNF inhibits neurodegenerative disease-associated asparaginyl endopeptidase activity via phosphorylation by AKT.

Wang ZH, Wu W, Kang SS, Liu X, Wu Z, Peng J, Yu SP, Manfredsson FP, Sandoval IM, Liu X, Wang JZ, Ye K. Wang ZH, et al. Among authors: wang jz. JCI Insight. 2018 Aug 23;3(16):e99007. doi: 10.1172/jci.insight.99007. eCollection 2018 Aug 23. JCI Insight. 2018. PMID: 30135302 Free PMC article.

9

Delta-secretase (AEP) mediates tau-splicing imbalance and accelerates cognitive decline in tauopathies.

Wang ZH, Liu P, Liu X, Yu SP, Wang JZ, Ye K. Wang ZH, et al. J Exp Med. 2018 Dec 3;215(12):3038-3056. doi: 10.1084/jem.20180539. Epub 2018 Oct 29. J Exp Med. 2018. PMID: 30373880 Free PMC article.

10

δ-Secretase-cleaved Tau stimulates Aβ production via upregulating STAT1-BACE1 signaling in Alzheimer's disease.

Zhang Z, Li XG, Wang ZH, Song M, Yu SP, Kang SS, Liu X, Zhang Z, Xie M, Liu GP, Wang JZ, Ye K. Zhang Z, et al. Among authors: wang zh, wang jz. Mol Psychiatry. 2021 Feb;26(2):586-603. doi: 10.1038/s41380-018-0286-z. Epub 2018 Oct 31. Mol Psychiatry. 2021. PMID: 30382187 Free PMC article.

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