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A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex.
Chatrikhi R, Feeney CF, Pulvino MJ, Alachouzos G, MacRae AJ, Falls Z, Rai S, Brennessel WW, Jenkins JL, Walter MJ, Graubert TA, Samudrala R, Jurica MS, Frontier AJ, Kielkopf CL. Chatrikhi R, et al. Among authors: pulvino mj. Cell Chem Biol. 2021 Aug 19;28(8):1145-1157.e6. doi: 10.1016/j.chembiol.2021.02.007. Epub 2021 Mar 8. Cell Chem Biol. 2021. PMID: 33689684 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33453965
Protein kinase Cβ is required for lupus development in Sle mice.
Oleksyn D, Pulvino M, Zhao J, Misra R, Vosoughi A, Jenks S, Tipton C, Lund F, Schwartz G, Goldman B, Mohan C, Mehta K, Mehta M, Leitgets M, Sanz I, Chen L. Oleksyn D, et al. Arthritis Rheum. 2013 Apr;65(4):1022-31. doi: 10.1002/art.37825. Arthritis Rheum. 2013. PMID: 23280626 Free PMC article.
Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline.
Pulvino M, Chen L, Oleksyn D, Li J, Compitello G, Rossi R, Spence S, Balakrishnan V, Jordan C, Poligone B, Casulo C, Burack R, Shapiro JL, Bernstein S, Friedberg JW, Deshaies RJ, Land H, Zhao J. Pulvino M, et al. Oncotarget. 2015 Jun 20;6(17):14796-813. doi: 10.18632/oncotarget.4193. Oncotarget. 2015. PMID: 26142707 Free PMC article.
13 results