Wen W - Search Results

1

A conformational switch driven by phosphorylation regulates the activity of the evolutionarily conserved SNARE Ykt6.

McGrath K, Agarwal S, Tonelli M, Dergai M, Gaeta AL, Shum AK, Lacoste J, Zhang Y, Wen W, Chung D, Wiersum G, Shevade A, Zaichick S, van Rossum DB, Shuvalova L, Savas JN, Kuchin S, Taipale M, Caldwell KA, Caldwell GA, Fasshauer D, Caraveo G. McGrath K, et al. Among authors: wen w. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2016730118. doi: 10.1073/pnas.2016730118. Proc Natl Acad Sci U S A. 2021. PMID: 33723042 Free PMC article.

2

Lipid-Induced conformational switch controls fusion activity of longin domain SNARE Ykt6.

Wen W, Yu J, Pan L, Wei Z, Weng J, Wang W, Ong YS, Tran TH, Hong W, Zhang M. Wen W, et al. Mol Cell. 2010 Feb 12;37(3):383-95. doi: 10.1016/j.molcel.2010.01.024. Mol Cell. 2010. PMID: 20159557 Free article.

3

Phosphorylation of DCC by ERK2 is facilitated by direct docking of the receptor P1 domain to the kinase.

Ma W, Shang Y, Wei Z, Wen W, Wang W, Zhang M. Ma W, et al. Among authors: wen w. Structure. 2010 Nov 10;18(11):1502-11. doi: 10.1016/j.str.2010.08.011. Structure. 2010. PMID: 21070949 Free article.

4

Crystal structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Gαi.

Jia M, Li J, Zhu J, Wen W, Zhang M, Wang W. Jia M, et al. Among authors: wen w. J Biol Chem. 2012 Oct 26;287(44):36766-76. doi: 10.1074/jbc.M112.391607. Epub 2012 Sep 5. J Biol Chem. 2012. PMID: 22952234 Free PMC article.

5

Structural and biochemical characterization of the interaction between LGN and Frmpd1.

Pan Z, Shang Y, Jia M, Zhang L, Xia C, Zhang M, Wang W, Wen W. Pan Z, et al. Among authors: wen w. J Mol Biol. 2013 Mar 25;425(6):1039-49. doi: 10.1016/j.jmb.2013.01.003. Epub 2013 Jan 11. J Mol Biol. 2013. PMID: 23318951

6

Structural determinants controlling 14-3-3 recruitment to the endocytic adaptor Numb and dissociation of the Numb·α-adaptin complex.

Chen X, Liu Z, Shan Z, Yao W, Gu A, Wen W. Chen X, et al. Among authors: wen w. J Biol Chem. 2018 Mar 16;293(11):4149-4158. doi: 10.1074/jbc.RA117.000897. Epub 2018 Jan 30. J Biol Chem. 2018. PMID: 29382713 Free PMC article.

7

Feedback regulation of ubiquitination and phase separation of HECT E3 ligases.

Li J, Zhu K, Gu A, Zhang Y, Huang S, Hu R, Hu W, Lei QY, Wen W. Li J, et al. Among authors: wen w. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2302478120. doi: 10.1073/pnas.2302478120. Epub 2023 Aug 7. Proc Natl Acad Sci U S A. 2023. PMID: 37549262 Free PMC article.

8

Reply to Eichbichler et al.: Phase separation boosts HECT E3-mediated polyubiquitination.

Zhu K, Li J, Wen W. Zhu K, et al. Among authors: wen w. Proc Natl Acad Sci U S A. 2024 Apr 2;121(14):e2403169121. doi: 10.1073/pnas.2403169121. Epub 2024 Mar 25. Proc Natl Acad Sci U S A. 2024. PMID: 38527202 Free PMC article. No abstract available.

9

Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules.

Zhu J, Shang Y, Xia C, Wang W, Wen W, Zhang M. Zhu J, et al. Among authors: wen w. EMBO J. 2011 Nov 25;30(24):4986-97. doi: 10.1038/emboj.2011.428. EMBO J. 2011. PMID: 22117215 Free PMC article.

10

An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs.

Pan Z, Zhu J, Shang Y, Wei Z, Jia M, Xia C, Wen W, Wang W, Zhang M. Pan Z, et al. Among authors: wen w. Structure. 2013 Jun 4;21(6):1007-17. doi: 10.1016/j.str.2013.04.005. Epub 2013 May 9. Structure. 2013. PMID: 23665171 Free article.

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