Chiang JJ - Search Results

1

ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity.

Liu G, Lee JH, Parker ZM, Acharya D, Chiang JJ, van Gent M, Riedl W, Davis-Gardner ME, Wies E, Chiang C, Gack MU. Liu G, et al. Among authors: chiang jj, chiang c. Nat Microbiol. 2021 Apr;6(4):467-478. doi: 10.1038/s41564-021-00884-1. Epub 2021 Mar 16. Nat Microbiol. 2021. PMID: 33727702 Free PMC article.

2

ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease.

Liu G, Lee JH, Parker ZM, Acharya D, Chiang JJ, van Gent M, Riedl W, Davis-Gardner ME, Wies E, Chiang C, Gack MU. Liu G, et al. Among authors: chiang jj, chiang c. bioRxiv [Preprint]. 2020 Oct 27:2020.10.26.356048. doi: 10.1101/2020.10.26.356048. bioRxiv. 2020. Update in: Nat Microbiol. 2021 Apr;6(4):467-478. doi: 10.1038/s41564-021-00884-1 PMID: 33140045 Free PMC article. Updated. Preprint.

3

The US3 Kinase of Herpes Simplex Virus Phosphorylates the RNA Sensor RIG-I To Suppress Innate Immunity.

van Gent M, Chiang JJ, Muppala S, Chiang C, Azab W, Kattenhorn L, Knipe DM, Osterrieder N, Gack MU. van Gent M, et al. Among authors: chiang jj, chiang c. J Virol. 2022 Feb 23;96(4):e0151021. doi: 10.1128/JVI.01510-21. Epub 2021 Dec 22. J Virol. 2022. PMID: 34935440 Free PMC article.

4

Regulation of RIG-I-like receptor signaling by host and viral proteins.

Chiang JJ, Davis ME, Gack MU. Chiang JJ, et al. Cytokine Growth Factor Rev. 2014 Oct;25(5):491-505. doi: 10.1016/j.cytogfr.2014.06.005. Epub 2014 Jun 21. Cytokine Growth Factor Rev. 2014. PMID: 25023063 Free PMC article. Review.

5

Reading the fine print: sequence-specific activation of cGAS.

Chiang JJ, Gack MU. Chiang JJ, et al. Nat Immunol. 2015 Oct;16(10):1009-10. doi: 10.1038/ni.3274. Nat Immunol. 2015. PMID: 26382862 No abstract available.

6

Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.

Chiang JJ, Sparrer KMJ, van Gent M, Lässig C, Huang T, Osterrieder N, Hopfner KP, Gack MU. Chiang JJ, et al. Nat Immunol. 2018 Jan;19(1):53-62. doi: 10.1038/s41590-017-0005-y. Epub 2017 Nov 27. Nat Immunol. 2018. PMID: 29180807 Free PMC article.

7

The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25's RNA Binding Ability.

Chiang C, Dvorkin S, Chiang JJ, Potter RB, Gack MU. Chiang C, et al. Among authors: chiang jj. mBio. 2021 Apr 13;12(2):e00620-21. doi: 10.1128/mBio.00620-21. mBio. 2021. PMID: 33849980 Free PMC article.

8

Crystal structure of the TRIM25 B30.2 (PRYSPRY) domain: a key component of antiviral signalling.

D'Cruz AA, Kershaw NJ, Chiang JJ, Wang MK, Nicola NA, Babon JJ, Gack MU, Nicholson SE. D'Cruz AA, et al. Among authors: chiang jj. Biochem J. 2013 Dec 1;456(2):231-40. doi: 10.1042/BJ20121425. Biochem J. 2013. PMID: 24015671 Free PMC article.

9

TRIM25 Binds RNA to Modulate Cellular Anti-viral Defense.

Sanchez JG, Sparrer KMJ, Chiang C, Reis RA, Chiang JJ, Zurenski MA, Wan Y, Gack MU, Pornillos O. Sanchez JG, et al. Among authors: chiang jj, chiang c. J Mol Biol. 2018 Dec 7;430(24):5280-5293. doi: 10.1016/j.jmb.2018.10.003. Epub 2018 Oct 17. J Mol Biol. 2018. PMID: 30342007 Free PMC article.

10

Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.

Sanchez JG, Chiang JJ, Sparrer KMJ, Alam SL, Chi M, Roganowicz MD, Sankaran B, Gack MU, Pornillos O. Sanchez JG, et al. Among authors: chiang jj. Cell Rep. 2016 Aug 2;16(5):1315-1325. doi: 10.1016/j.celrep.2016.06.070. Epub 2016 Jul 14. Cell Rep. 2016. PMID: 27425606 Free PMC article.

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