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Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes.
Ravindra NG, Alfajaro MM, Gasque V, Huston NC, Wan H, Szigeti-Buck K, Yasumoto Y, Greaney AM, Habet V, Chow RD, Chen JS, Wei J, Filler RB, Wang B, Wang G, Niklason LE, Montgomery RR, Eisenbarth SC, Chen S, Williams A, Iwasaki A, Horvath TL, Foxman EF, Pierce RW, Pyle AM, van Dijk D, Wilen CB. Ravindra NG, et al. Among authors: chen js, chen s. PLoS Biol. 2021 Mar 17;19(3):e3001143. doi: 10.1371/journal.pbio.3001143. eCollection 2021 Mar. PLoS Biol. 2021. PMID: 33730024 Free PMC article.
Two-Factor Authentication for Type 2 Immunity.
Chen JS, Eisenbarth SC. Chen JS, et al. Immunity. 2018 Sep 18;49(3):381-383. doi: 10.1016/j.immuni.2018.08.020. Immunity. 2018. PMID: 30231976 Free article.
Identification of a T follicular helper cell subset that drives anaphylactic IgE.
Gowthaman U, Chen JS, Zhang B, Flynn WF, Lu Y, Song W, Joseph J, Gertie JA, Xu L, Collet MA, Grassmann JDS, Simoneau T, Chiang D, Berin MC, Craft JE, Weinstein JS, Williams A, Eisenbarth SC. Gowthaman U, et al. Among authors: chen js. Science. 2019 Aug 30;365(6456):eaaw6433. doi: 10.1126/science.aaw6433. Epub 2019 Aug 1. Science. 2019. PMID: 31371561 Free PMC article.
Regulation of IgE by T follicular helper cells.
Gowthaman U, Chen JS, Eisenbarth SC. Gowthaman U, et al. Among authors: chen js. J Leukoc Biol. 2020 Mar;107(3):409-418. doi: 10.1002/JLB.3RI1219-425R. Epub 2020 Jan 22. J Leukoc Biol. 2020. PMID: 31965637 Free PMC article. Review.
Flow cytometric identification of Tfh13 cells in mouse and human.
Chen JS, Grassmann JDS, Gowthaman U, Olyha SJ, Simoneau T, Berin MC, Eisenbarth SC, Williams A. Chen JS, et al. J Allergy Clin Immunol. 2021 Feb;147(2):470-483. doi: 10.1016/j.jaci.2020.04.063. Epub 2020 Jul 21. J Allergy Clin Immunol. 2021. PMID: 32709424 Free PMC article. Review.
Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection.
Wei J, Alfajaro MM, Hanna RE, DeWeirdt PC, Strine MS, Lu-Culligan WJ, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Gasque V, de Miguel F, Chen H, Oguntuyo K, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach B, Politi K, van Dijk D, Simon MD, Yan Q, Doench JG, Wilen CB. Wei J, et al. Among authors: chen js, chen h. bioRxiv [Preprint]. 2020 Jun 17:2020.06.16.155101. doi: 10.1101/2020.06.16.155101. bioRxiv. 2020. Update in: Cell. 2021 Jan 7;184(1):76-91.e13. doi: 10.1016/j.cell.2020.10.028 PMID: 32869025 Free PMC article. Updated. Preprint.
A web tool for the design of prime-editing guide RNAs.
Chow RD, Chen JS, Shen J, Chen S. Chow RD, et al. Among authors: chen js, chen s. Nat Biomed Eng. 2021 Feb;5(2):190-194. doi: 10.1038/s41551-020-00622-8. Epub 2020 Sep 28. Nat Biomed Eng. 2021. PMID: 32989284 Free PMC article.
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.
Wei J, Alfajaro MM, DeWeirdt PC, Hanna RE, Lu-Culligan WJ, Cai WL, Strine MS, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Ravindra NG, Gasque V, de Miguel FJ, Patil A, Chen H, Oguntuyo KY, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach BD, Politi K, van Dijk D, Kadoch C, Simon MD, Yan Q, Doench JG, Wilen CB. Wei J, et al. Among authors: chen js, chen h. Cell. 2021 Jan 7;184(1):76-91.e13. doi: 10.1016/j.cell.2020.10.028. Epub 2020 Oct 20. Cell. 2021. PMID: 33147444 Free PMC article.
3,062 results