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Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes.
Ravindra NG, Alfajaro MM, Gasque V, Huston NC, Wan H, Szigeti-Buck K, Yasumoto Y, Greaney AM, Habet V, Chow RD, Chen JS, Wei J, Filler RB, Wang B, Wang G, Niklason LE, Montgomery RR, Eisenbarth SC, Chen S, Williams A, Iwasaki A, Horvath TL, Foxman EF, Pierce RW, Pyle AM, van Dijk D, Wilen CB. Ravindra NG, et al. Among authors: wang g, wang b. PLoS Biol. 2021 Mar 17;19(3):e3001143. doi: 10.1371/journal.pbio.3001143. eCollection 2021 Mar. PLoS Biol. 2021. PMID: 33730024 Free PMC article.
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium.
Ravindra NG, Alfajaro MM, Gasque V, Habet V, Wei J, Filler RB, Huston NC, Wan H, Szigeti-Buck K, Wang B, Wang G, Montgomery RR, Eisenbarth SC, Williams A, Pyle AM, Iwasaki A, Horvath TL, Foxman EF, Pierce RW, van Dijk D, Wilen CB. Ravindra NG, et al. Among authors: wang g, wang b. bioRxiv [Preprint]. 2020 Jul 13:2020.05.06.081695. doi: 10.1101/2020.05.06.081695. bioRxiv. 2020. Update in: PLoS Biol. 2021 Mar 17;19(3):e3001143. doi: 10.1371/journal.pbio.3001143 PMID: 32511382 Free PMC article. Updated. Preprint.
Neuroinvasion of SARS-CoV-2 in human and mouse brain.
Song E, Zhang C, Israelow B, Lu-Culligan A, Prado AV, Skriabine S, Lu P, Weizman OE, Liu F, Dai Y, Szigeti-Buck K, Yasumoto Y, Wang G, Castaldi C, Heltke J, Ng E, Wheeler J, Alfajaro MM, Levavasseur E, Fontes B, Ravindra NG, Van Dijk D, Mane S, Gunel M, Ring A, Kazmi SAJ, Zhang K, Wilen CB, Horvath TL, Plu I, Haik S, Thomas JL, Louvi A, Farhadian SF, Huttner A, Seilhean D, Renier N, Bilguvar K, Iwasaki A. Song E, et al. Among authors: wang g. bioRxiv [Preprint]. 2020 Sep 8:2020.06.25.169946. doi: 10.1101/2020.06.25.169946. bioRxiv. 2020. Update in: J Exp Med. 2021 Mar 1;218(3):e20202135. doi: 10.1084/jem.20202135 PMID: 32935108 Free PMC article. Updated. Preprint.
Neuroinvasion of SARS-CoV-2 in human and mouse brain.
Song E, Zhang C, Israelow B, Lu-Culligan A, Prado AV, Skriabine S, Lu P, Weizman OE, Liu F, Dai Y, Szigeti-Buck K, Yasumoto Y, Wang G, Castaldi C, Heltke J, Ng E, Wheeler J, Alfajaro MM, Levavasseur E, Fontes B, Ravindra NG, Van Dijk D, Mane S, Gunel M, Ring A, Kazmi SAJ, Zhang K, Wilen CB, Horvath TL, Plu I, Haik S, Thomas JL, Louvi A, Farhadian SF, Huttner A, Seilhean D, Renier N, Bilguvar K, Iwasaki A. Song E, et al. Among authors: wang g. J Exp Med. 2021 Mar 1;218(3):e20202135. doi: 10.1084/jem.20202135. J Exp Med. 2021. PMID: 33433624 Free PMC article.
Magnitude and timing of the antiviral response determine SARS-CoV-2 replication early in infection.
Cheemarla NR, Watkins TA, Mihaylova VT, Wang B, Zhao D, Wang G, Landry ML, Foxman EF. Cheemarla NR, et al. Among authors: wang g, wang b. medRxiv [Preprint]. 2021 Jan 27:2021.01.22.21249812. doi: 10.1101/2021.01.22.21249812. medRxiv. 2021. Update in: J Exp Med. 2021 Aug 2;218(8):e20210583. doi: 10.1084/jem.20210583 PMID: 33532783 Free PMC article. Updated. Preprint.
Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Peng L, Hu Y, Mankowski MC, Ren P, Chen RE, Wei J, Zhao M, Li T, Tripler T, Ye L, Chow RD, Fang Z, Wu C, Dong MB, Cook M, Wang G, Clark P, Nelson B, Klein D, Sutton R, Diamond MS, Wilen CB, Xiong Y, Chen S. Peng L, et al. Among authors: wang g. bioRxiv [Preprint]. 2021 Dec 24:2021.12.21.473733. doi: 10.1101/2021.12.21.473733. bioRxiv. 2021. Update in: Nat Commun. 2022 Mar 28;13(1):1638. doi: 10.1038/s41467-022-29288-3 PMID: 34981065 Free PMC article. Updated. Preprint.
Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19.
Unterman A, Sumida TS, Nouri N, Yan X, Zhao AY, Gasque V, Schupp JC, Asashima H, Liu Y, Cosme C Jr, Deng W, Chen M, Raredon MSB, Hoehn KB, Wang G, Wang Z, DeIuliis G, Ravindra NG, Li N, Castaldi C, Wong P, Fournier J, Bermejo S, Sharma L, Casanovas-Massana A, Vogels CBF, Wyllie AL, Grubaugh ND, Melillo A, Meng H, Stein Y, Minasyan M, Mohanty S, Ruff WE, Cohen I, Raddassi K; Yale IMPACT Research Team; Niklason LE, Ko AI, Montgomery RR, Farhadian SF, Iwasaki A, Shaw AC, van Dijk D, Zhao H, Kleinstein SH, Hafler DA, Kaminski N, Dela Cruz CS. Unterman A, et al. Among authors: wang g, wang z. Nat Commun. 2022 Jan 21;13(1):440. doi: 10.1038/s41467-021-27716-4. Nat Commun. 2022. PMID: 35064122 Free PMC article.
Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Peng L, Hu Y, Mankowski MC, Ren P, Chen RE, Wei J, Zhao M, Li T, Tripler T, Ye L, Chow RD, Fang Z, Wu C, Dong MB, Cook M, Wang G, Clark P, Nelson B, Klein D, Sutton R, Diamond MS, Wilen CB, Xiong Y, Chen S. Peng L, et al. Among authors: wang g. Nat Commun. 2022 Mar 28;13(1):1638. doi: 10.1038/s41467-022-29288-3. Nat Commun. 2022. PMID: 35347138 Free PMC article.
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