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A Drosophila platform identifies a novel, personalized therapy for a patient with adenoid cystic carcinoma.
Bangi E, Smibert P, Uzilov AV, Teague AG, Gopinath S, Antipin Y, Chen R, Hecht C, Gruszczynski N, Yon WJ, Malyshev D, Laspina D, Selkridge I, Wang H, Gomez J, Mascarenhas J, Moe AS, Lau CY, Taik P, Pandya C, Sung M, Kim S, Yum K, Sebra R, Donovan M, Misiukiewicz K, Ang C, Schadt EE, Posner MR, Cagan RL. Bangi E, et al. Among authors: chen r. iScience. 2021 Feb 20;24(3):102212. doi: 10.1016/j.isci.2021.102212. eCollection 2021 Mar 19. iScience. 2021. PMID: 33733072 Free PMC article.
Genomic profiling reveals mutational landscape in parathyroid carcinomas.
Pandya C, Uzilov AV, Bellizzi J, Lau CY, Moe AS, Strahl M, Hamou W, Newman LC, Fink MY, Antipin Y, Yu W, Stevenson M, Cavaco BM, Teh BT, Thakker RV, Morreau H, Schadt EE, Sebra R, Li SD, Arnold A, Chen R. Pandya C, et al. Among authors: chen r. JCI Insight. 2017 Mar 23;2(6):e92061. doi: 10.1172/jci.insight.92061. JCI Insight. 2017. PMID: 28352668 Free PMC article.
USP8 and TP53 Drivers are Associated with CNV in a Corticotroph Adenoma Cohort Enriched for Aggressive Tumors.
Uzilov AV, Taik P, Cheesman KC, Javanmard P, Ying K, Roehnelt A, Wang H, Fink MY, Lau CY, Moe AS, Villar J, Bederson JB, Stewart AF, Donovan MJ, Mahajan M, Sebra R, Post KD, Chen R, Geer EB. Uzilov AV, et al. Among authors: chen r. J Clin Endocrinol Metab. 2021 Mar 8;106(3):826-842. doi: 10.1210/clinem/dgaa853. J Clin Endocrinol Metab. 2021. PMID: 33221858
Parafibromin Abnormalities in Ossifying Fibroma.
Costa-Guda J, Pandya C, Strahl M, Taik P, Sebra R, Chen R, Uzilov AV, Arnold A. Costa-Guda J, et al. Among authors: chen r. J Endocr Soc. 2021 May 8;5(7):bvab087. doi: 10.1210/jendso/bvab087. eCollection 2021 Jul 1. J Endocr Soc. 2021. PMID: 34159287 Free PMC article.
Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.
Wang H, Bender A, Wang P, Karakose E, Inabnet WB, Libutti SK, Arnold A, Lambertini L, Stang M, Chen H, Kasai Y, Mahajan M, Kinoshita Y, Fernandez-Ranvier G, Becker TC, Takane KK, Walker LA, Saul S, Chen R, Scott DK, Ferrer J, Antipin Y, Donovan M, Uzilov AV, Reva B, Schadt EE, Losic B, Argmann C, Stewart AF. Wang H, et al. Among authors: chen r, chen h. Nat Commun. 2017 Oct 3;8(1):767. doi: 10.1038/s41467-017-00992-9. Nat Commun. 2017. PMID: 28974674 Free PMC article.
Personalized Circulating Tumor DNA Biomarkers Dynamically Predict Treatment Response and Survival In Gynecologic Cancers.
Pereira E, Camacho-Vanegas O, Anand S, Sebra R, Catalina Camacho S, Garnar-Wortzel L, Nair N, Moshier E, Wooten M, Uzilov A, Chen R, Prasad-Hayes M, Zakashansky K, Beddoe AM, Schadt E, Dottino P, Martignetti JA. Pereira E, et al. Among authors: chen r. PLoS One. 2015 Dec 30;10(12):e0145754. doi: 10.1371/journal.pone.0145754. eCollection 2015. PLoS One. 2015. PMID: 26717006 Free PMC article.
Phase 2 Trial of Gemcitabine, Cisplatin, plus Ipilimumab in Patients with Metastatic Urothelial Cancer and Impact of DNA Damage Response Gene Mutations on Outcomes.
Galsky MD, Wang H, Hahn NM, Twardowski P, Pal SK, Albany C, Fleming MT, Starodub A, Hauke RJ, Yu M, Zhao Q, Sonpavde G, Donovan MJ, Patel VG, Sfakianos JP, Domingo-Domenech J, Oh WK, Akers N, Losic B, Gnjatic S, Schadt EE, Chen R, Kim-Schulze S, Bhardwaj N, Uzilov AV. Galsky MD, et al. Among authors: chen r. Eur Urol. 2018 May;73(5):751-759. doi: 10.1016/j.eururo.2017.12.001. Epub 2017 Dec 13. Eur Urol. 2018. PMID: 29248319 Clinical Trial.
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