Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

571 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Identification of potent farnesoid X receptor (FXR) antagonist showing favorable PK profile and distribution toward target tissues: Comprehensive understanding of structure-activity relationship of FXR antagonists.
Teno N, Yamashita Y, Masuda A, Iguchi Y, Oda K, Fujimori K, Hiramoto T, Nishimaki-Mogami T, Une M, Gohda K. Teno N, et al. Among authors: iguchi y. Bioorg Med Chem. 2019 Jun 1;27(11):2220-2227. doi: 10.1016/j.bmc.2019.04.029. Epub 2019 Apr 20. Bioorg Med Chem. 2019. PMID: 31029550
Design and identification of a new farnesoid X receptor (FXR) partial agonist by computational structure-activity relationship analysis: Ligand-induced H8 helix fluctuation in the ligand-binding domain of FXR may lead to partial agonism.
Gohda K, Iguchi Y, Masuda A, Fujimori K, Yamashita Y, Teno N. Gohda K, et al. Among authors: iguchi y. Bioorg Med Chem Lett. 2021 Jun 1;41:128026. doi: 10.1016/j.bmcl.2021.128026. Epub 2021 Apr 9. Bioorg Med Chem Lett. 2021. PMID: 33839252
571 results