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Page 1
ZFTA Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors.
Kupp R, Ruff L, Terranova S, Nathan E, Ballereau S, Stark R, Sekhar Reddy Chilamakuri C, Hoffmann N, Wickham-Rahrmann K, Widdess M, Arabzade A, Zhao Y, Varadharajan S, Zheng T, Murugesan M, Pfister SM, Kawauchi D, Pajtler KW, Deneen B, Mack SC, Masih KE, Gryder BE, Khan J, Gilbertson RJ. Kupp R, et al. Among authors: deneen b. Cancer Discov. 2021 Sep;11(9):2216-2229. doi: 10.1158/2159-8290.CD-20-1052. Epub 2021 Mar 19. Cancer Discov. 2021. PMID: 33741711 Free PMC article.
ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.
Arabzade A, Zhao Y, Varadharajan S, Chen HC, Jessa S, Rivas B, Stuckert AJ, Solis M, Kardian A, Tlais D, Golbourn BJ, Stanton AJ, Chan YS, Olson C, Karlin KL, Kong K, Kupp R, Hu B, Injac SG, Ngo M, Wang PR, De León LA, Sahm F, Kawauchi D, Pfister SM, Lin CY, Hodges HC, Singh I, Westbrook TF, Chintagumpala MM, Blaney SM, Parsons DW, Pajtler KW, Agnihotri S, Gilbertson RJ, Yi J, Jabado N, Kleinman CL, Bertrand KC, Deneen B, Mack SC. Arabzade A, et al. Among authors: deneen b. Cancer Discov. 2021 Sep;11(9):2200-2215. doi: 10.1158/2159-8290.CD-20-1066. Epub 2021 Mar 19. Cancer Discov. 2021. PMID: 33741710 Free PMC article.
Sox9 directs divergent epigenomic states in brain tumor subtypes.
Sardar D, Chen HC, Reyes A, Varadharajan S, Jain A, Mohila C, Curry R, Lozzi B, Rajendran K, Cervantes A, Yu K, Jalali A, Rao G, Mack SC, Deneen B. Sardar D, et al. Among authors: deneen b. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2202015119. doi: 10.1073/pnas.2202015119. Epub 2022 Jul 15. Proc Natl Acad Sci U S A. 2022. PMID: 35858326 Free PMC article.
Histone serotonylation regulates ependymoma tumorigenesis.
Chen HC, He P, McDonald M, Williamson MR, Varadharajan S, Lozzi B, Woo J, Choi DJ, Sardar D, Huang-Hobbs E, Sun H, Ippagunta SM, Jain A, Rao G, Merchant TE, Ellison DW, Noebels JL, Bertrand KC, Mack SC, Deneen B. Chen HC, et al. Among authors: deneen b. Nature. 2024 Aug;632(8026):903-910. doi: 10.1038/s41586-024-07751-z. Epub 2024 Jul 31. Nature. 2024. PMID: 39085609
Next Directions in the Neuroscience of Cancers Arising outside the CNS.
Amit M, Anastasaki C, Dantzer R, Demir IE, Deneen B, Dixon KO, Egeblad M, Gibson EM, Hervey-Jumper SL, Hondermarck H, Magnon C, Monje M, Na'ara S, Pan Y, Repasky EA, Scheff NN, Sloan EK, Talbot S, Tracey KJ, Trotman LC, Valiente M, Van Aelst L, Venkataramani V, Venkatesh HS, Vermeer PD, Winkler F, Wong RJ, Gutmann DH, Borniger JC. Amit M, et al. Among authors: deneen b. Cancer Discov. 2024 Apr 4;14(4):669-673. doi: 10.1158/2159-8290.CD-23-1495. Cancer Discov. 2024. PMID: 38571430
Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.
Danussi C, Bose P, Parthasarathy PT, Silberman PC, Van Arnam JS, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang FF, Creighton CJ, Deneen B, Miller CR, Picketts DJ, Kannan K, Huse JT. Danussi C, et al. Among authors: deneen b. Nat Commun. 2018 Mar 13;9(1):1057. doi: 10.1038/s41467-018-03476-6. Nat Commun. 2018. PMID: 29535300 Free PMC article.
POT1 Regulates Proliferation and Confers Sexual Dimorphism in Glioma.
Jalali A, Yu K, Beechar V, Bosquez Huerta NA, Grichuk A, Mehra D, Lozzi B, Kong K, Scott KL, Rao G, Bainbridge MN, Bondy ML, Deneen B. Jalali A, et al. Among authors: deneen b. Cancer Res. 2021 May 15;81(10):2703-2713. doi: 10.1158/0008-5472.CAN-20-3755. Epub 2021 Mar 29. Cancer Res. 2021. PMID: 33782098 Free PMC article.
102 results