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Page 1
Red blood cell mannoses as phagocytic ligands mediating both sickle cell anaemia and malaria resistance.
Cao H, Antonopoulos A, Henderson S, Wassall H, Brewin J, Masson A, Shepherd J, Konieczny G, Patel B, Williams ML, Davie A, Forrester MA, Hall L, Minter B, Tampakis D, Moss M, Lennon C, Pickford W, Erwig L, Robertson B, Dell A, Brown GD, Wilson HM, Rees DC, Haslam SM, Alexandra Rowe J, Barker RN, Vickers MA. Cao H, et al. Among authors: brown gd. Nat Commun. 2021 Mar 19;12(1):1792. doi: 10.1038/s41467-021-21814-z. Nat Commun. 2021. PMID: 33741926 Free PMC article.
Lactate signalling regulates fungal β-glucan masking and immune evasion.
Ballou ER, Avelar GM, Childers DS, Mackie J, Bain JM, Wagener J, Kastora SL, Panea MD, Hardison SE, Walker LA, Erwig LP, Munro CA, Gow NA, Brown GD, MacCallum DM, Brown AJ. Ballou ER, et al. Among authors: brown aj, brown gd. Nat Microbiol. 2016 Dec 12;2:16238. doi: 10.1038/nmicrobiol.2016.238. Nat Microbiol. 2016. PMID: 27941860 Free PMC article.
Immune cells fold and damage fungal hyphae.
Bain JM, Alonso MF, Childers DS, Walls CA, Mackenzie K, Pradhan A, Lewis LE, Louw J, Avelar GM, Larcombe DE, Netea MG, Gow NAR, Brown GD, Erwig LP, Brown AJP. Bain JM, et al. Among authors: brown gd, brown ajp. Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2020484118. doi: 10.1073/pnas.2020484118. Proc Natl Acad Sci U S A. 2021. PMID: 33876755 Free PMC article.
Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus.
Stappers MHT, Clark AE, Aimanianda V, Bidula S, Reid DM, Asamaphan P, Hardison SE, Dambuza IM, Valsecchi I, Kerscher B, Plato A, Wallace CA, Yuecel R, Hebecker B, da Glória Teixeira Sousa M, Cunha C, Liu Y, Feizi T, Brakhage AA, Kwon-Chung KJ, Gow NAR, Zanda M, Piras M, Zanato C, Jaeger M, Netea MG, van de Veerdonk FL, Lacerda JF, Campos A, Carvalho A, Willment JA, Latgé JP, Brown GD. Stappers MHT, et al. Among authors: brown gd. Nature. 2018 Mar 15;555(7696):382-386. doi: 10.1038/nature25974. Epub 2018 Feb 28. Nature. 2018. PMID: 29489751 Free PMC article.
Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity.
Gonçalves SM, Duarte-Oliveira C, Campos CF, Aimanianda V, Ter Horst R, Leite L, Mercier T, Pereira P, Fernández-García M, Antunes D, Rodrigues CS, Barbosa-Matos C, Gaifem J, Mesquita I, Marques A, Osório NS, Torrado E, Rodrigues F, Costa S, Joosten LA, Lagrou K, Maertens J, Lacerda JF, Campos A Jr, Brown GD, Brakhage AA, Barbas C, Silvestre R, van de Veerdonk FL, Chamilos G, Netea MG, Latgé JP, Cunha C, Carvalho A. Gonçalves SM, et al. Among authors: brown gd. Nat Commun. 2020 May 8;11(1):2282. doi: 10.1038/s41467-020-16120-z. Nat Commun. 2020. PMID: 32385235 Free PMC article.
581 results