Sunahara RK - Search Results

1

Delineating the conformational landscape of the adenosine A_2A receptor during G protein coupling.

Huang SK, Pandey A, Tran DP, Villanueva NL, Kitao A, Sunahara RK, Sljoka A, Prosser RS. Huang SK, et al. Among authors: sunahara rk. Cell. 2021 Apr 1;184(7):1884-1894.e14. doi: 10.1016/j.cell.2021.02.041. Epub 2021 Mar 19. Cell. 2021. PMID: 33743210 Free PMC article.

2

SIGNAL TRANSDUCTION. Structural basis for nucleotide exchange in heterotrimeric G proteins.

Dror RO, Mildorf TJ, Hilger D, Manglik A, Borhani DW, Arlow DH, Philippsen A, Villanueva N, Yang Z, Lerch MT, Hubbell WL, Kobilka BK, Sunahara RK, Shaw DE. Dror RO, et al. Among authors: sunahara rk. Science. 2015 Jun 19;348(6241):1361-5. doi: 10.1126/science.aaa5264. Science. 2015. PMID: 26089515 Free PMC article.

3

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.

Thomsen ARB, Plouffe B, Cahill TJ 3rd, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ. Thomsen ARB, et al. Among authors: sunahara rk. Cell. 2016 Aug 11;166(4):907-919. doi: 10.1016/j.cell.2016.07.004. Epub 2016 Aug 4. Cell. 2016. PMID: 27499021 Free PMC article.

4

In Situ Reconstitution of the Adenosine A_2A Receptor in Spontaneously Formed Synthetic Liposomes.

Brea RJ, Cole CM, Lyda BR, Ye L, Prosser RS, Sunahara RK, Devaraj NK. Brea RJ, et al. Among authors: sunahara rk. J Am Chem Soc. 2017 Mar 15;139(10):3607-3610. doi: 10.1021/jacs.6b12830. Epub 2017 Mar 6. J Am Chem Soc. 2017. PMID: 28263576 Free PMC article.

5

Mechanistic insights into allosteric regulation of the A_2A adenosine G protein-coupled receptor by physiological cations.

Ye L, Neale C, Sljoka A, Lyda B, Pichugin D, Tsuchimura N, Larda ST, Pomès R, García AE, Ernst OP, Sunahara RK, Prosser RS. Ye L, et al. Among authors: sunahara rk. Nat Commun. 2018 Apr 10;9(1):1372. doi: 10.1038/s41467-018-03314-9. Nat Commun. 2018. PMID: 29636462 Free PMC article.

6

Leveraging nonstructural data to predict structures and affinities of protein-ligand complexes.

Paggi JM, Belk JA, Hollingsworth SA, Villanueva N, Powers AS, Clark MJ, Chemparathy AG, Tynan JE, Lau TK, Sunahara RK, Dror RO. Paggi JM, et al. Among authors: sunahara rk. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2112621118. doi: 10.1073/pnas.2112621118. Proc Natl Acad Sci U S A. 2021. PMID: 34921117 Free PMC article.

7

Mapping the conformational landscape of the stimulatory heterotrimeric G protein.

Huang SK, Picard LP, Rahmatullah RSM, Pandey A, Van Eps N, Sunahara RK, Ernst OP, Sljoka A, Prosser RS. Huang SK, et al. Among authors: sunahara rk. Nat Struct Mol Biol. 2023 Apr;30(4):502-511. doi: 10.1038/s41594-023-00957-1. Epub 2023 Mar 30. Nat Struct Mol Biol. 2023. PMID: 36997760

8

Conformational changes in the G protein Gs induced by the β2 adrenergic receptor.

Chung KY, Rasmussen SG, Liu T, Li S, DeVree BT, Chae PS, Calinski D, Kobilka BK, Woods VL Jr, Sunahara RK. Chung KY, et al. Among authors: sunahara rk. Nature. 2011 Sep 28;477(7366):611-5. doi: 10.1038/nature10488. Nature. 2011. PMID: 21956331 Free PMC article.

9

Conformational biosensors reveal GPCR signalling from endosomes.

Irannejad R, Tomshine JC, Tomshine JR, Chevalier M, Mahoney JP, Steyaert J, Rasmussen SG, Sunahara RK, El-Samad H, Huang B, von Zastrow M. Irannejad R, et al. Among authors: sunahara rk. Nature. 2013 Mar 28;495(7442):534-8. doi: 10.1038/nature12000. Epub 2013 Mar 20. Nature. 2013. PMID: 23515162 Free PMC article.

10

Mechanistic insights into GPCR-G protein interactions.

Mahoney JP, Sunahara RK. Mahoney JP, et al. Among authors: sunahara rk. Curr Opin Struct Biol. 2016 Dec;41:247-254. doi: 10.1016/j.sbi.2016.11.005. Epub 2016 Nov 18. Curr Opin Struct Biol. 2016. PMID: 27871057 Free PMC article. Review.

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