Chen D - Search Results

1

Structure-Based Design of a Selective Class I Histone Deacetylase (HDAC) Near-Infrared (NIR) Probe for Epigenetic Regulation Detection in Triple-Negative Breast Cancer (TNBC).

Zhang K, Liu Z, Yao Y, Qiu Y, Li F, Chen D, Hamilton DJ, Li Z, Jiang S. Zhang K, et al. Among authors: chen d. J Med Chem. 2021 Apr 8;64(7):4020-4033. doi: 10.1021/acs.jmedchem.0c02161. Epub 2021 Mar 22. J Med Chem. 2021. PMID: 33745280

2

PQJS380: a novel lead compound to induce apoptosis in acute lymphoblastic leukemia cells.

Zhu X, Chen L, Jiang S, Chen C, Yao Y, Chen D, Xue H, Pan J. Zhu X, et al. Among authors: chen l, chen c, chen d. Cancer Biol Ther. 2014 Jan;15(1):119-27. doi: 10.4161/cbt.27145. Epub 2013 Nov 19. Cancer Biol Ther. 2014. PMID: 24253322 Free PMC article.

3

NAD(P)H:Quinone Oxidoreductase 1 (NQO1) as a Therapeutic and Diagnostic Target in Cancer.

Zhang K, Chen D, Ma K, Wu X, Hao H, Jiang S. Zhang K, et al. Among authors: chen d. J Med Chem. 2018 Aug 23;61(16):6983-7003. doi: 10.1021/acs.jmedchem.8b00124. Epub 2018 May 7. J Med Chem. 2018. PMID: 29712428 Review.

4

Discovery of trans-3-(pyridin-3-yl)acrylamide-derived sulfamides as potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitors for the potential treatment of cancer.

Zhang K, Ni Y, Chen J, Tu Z, Wu X, Chen D, Yao H, Jiang S. Zhang K, et al. Among authors: chen j, chen d. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1502-1506. doi: 10.1016/j.bmcl.2019.04.013. Epub 2019 Apr 8. Bioorg Med Chem Lett. 2019. PMID: 30992165

5

Targeting tropomyosin receptor kinase for cancer therapy.

Miao Q, Ma K, Chen D, Wu X, Jiang S. Miao Q, et al. Among authors: chen d. Eur J Med Chem. 2019 Aug 1;175:129-148. doi: 10.1016/j.ejmech.2019.04.053. Epub 2019 Apr 30. Eur J Med Chem. 2019. PMID: 31077998 Review.

6

Discovery of class I histone deacetylase inhibitors based on romidpesin with promising selectivity for cancer cells.

Zhang K, Yao Y, Tu Z, Liao C, Wang Z, Qiu Y, Chen D, Hamilton DJ, Li Z, Jiang S. Zhang K, et al. Among authors: chen d. Future Med Chem. 2020 Feb;12(4):311-323. doi: 10.4155/fmc-2019-0290. Epub 2019 Nov 29. Future Med Chem. 2020. PMID: 31782319

7

Dual nicotinamide phosphoribosyltransferase and epidermal growth factor receptor inhibitors for the treatment of cancer.

Zhang W, Zhang K, Yao Y, Liu Y, Ni Y, Liao C, Tu Z, Qiu Y, Wang D, Chen D, Qiang L, Li Z, Jiang S. Zhang W, et al. Among authors: chen d. Eur J Med Chem. 2021 Feb 5;211:113022. doi: 10.1016/j.ejmech.2020.113022. Epub 2020 Nov 13. Eur J Med Chem. 2021. PMID: 33239261

8

Novel Biphenyl Pyridines as Potent Small-Molecule Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.

Wang T, Cai S, Wang M, Zhang W, Zhang K, Chen D, Li Z, Jiang S. Wang T, et al. Among authors: chen d. J Med Chem. 2021 Jun 10;64(11):7390-7403. doi: 10.1021/acs.jmedchem.1c00010. Epub 2021 May 30. J Med Chem. 2021. PMID: 34056906

9

Recent Insights of Metformin on Hepatocellular Carcinoma (HCC).

Wang K, Zhang K, Zhang X, Chen D, Jiang S. Wang K, et al. Among authors: chen d. Mini Rev Med Chem. 2023;23(11):1154-1166. doi: 10.2174/1389557522666220623150717. Mini Rev Med Chem. 2023. PMID: 35747976 Review.

10

Synthesis and antitumor activities of novel 1,4-disubstituted phthalazine derivatives.

Zhang S, Zhao Y, Liu Y, Chen D, Lan W, Zhao Q, Dong C, Xia L, Gong P. Zhang S, et al. Among authors: chen d. Eur J Med Chem. 2010 Aug;45(8):3504-10. doi: 10.1016/j.ejmech.2010.05.016. Epub 2010 May 12. Eur J Med Chem. 2010. PMID: 20537434

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