Zhang K - Search Results

1

Structure-Based Design of a Selective Class I Histone Deacetylase (HDAC) Near-Infrared (NIR) Probe for Epigenetic Regulation Detection in Triple-Negative Breast Cancer (TNBC).

Zhang K, Liu Z, Yao Y, Qiu Y, Li F, Chen D, Hamilton DJ, Li Z, Jiang S. Zhang K, et al. J Med Chem. 2021 Apr 8;64(7):4020-4033. doi: 10.1021/acs.jmedchem.0c02161. Epub 2021 Mar 22. J Med Chem. 2021. PMID: 33745280

2

NAD(P)H:Quinone Oxidoreductase 1 (NQO1) as a Therapeutic and Diagnostic Target in Cancer.

Zhang K, Chen D, Ma K, Wu X, Hao H, Jiang S. Zhang K, et al. J Med Chem. 2018 Aug 23;61(16):6983-7003. doi: 10.1021/acs.jmedchem.8b00124. Epub 2018 May 7. J Med Chem. 2018. PMID: 29712428 Review.

3

Development of Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Signaling Pathway.

Wang T, Wu X, Guo C, Zhang K, Xu J, Li Z, Jiang S. Wang T, et al. Among authors: zhang k. J Med Chem. 2019 Feb 28;62(4):1715-1730. doi: 10.1021/acs.jmedchem.8b00990. Epub 2018 Oct 9. J Med Chem. 2019. PMID: 30247903 Review.

4

Discovery of trans-3-(pyridin-3-yl)acrylamide-derived sulfamides as potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitors for the potential treatment of cancer.

Zhang K, Ni Y, Chen J, Tu Z, Wu X, Chen D, Yao H, Jiang S. Zhang K, et al. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1502-1506. doi: 10.1016/j.bmcl.2019.04.013. Epub 2019 Apr 8. Bioorg Med Chem Lett. 2019. PMID: 30992165

5

Discovery of class I histone deacetylase inhibitors based on romidpesin with promising selectivity for cancer cells.

Zhang K, Yao Y, Tu Z, Liao C, Wang Z, Qiu Y, Chen D, Hamilton DJ, Li Z, Jiang S. Zhang K, et al. Future Med Chem. 2020 Feb;12(4):311-323. doi: 10.4155/fmc-2019-0290. Epub 2019 Nov 29. Future Med Chem. 2020. PMID: 31782319

6

Suppression of Musashi‑2 by the small compound largazole exerts inhibitory effects on malignant cells.

Wang M, Sun XY, Zhou YC, Zhang KJ, Lu YZ, Liu J, Huang YC, Wang GZ, Jiang S, Zhou GB. Wang M, et al. Int J Oncol. 2020 May;56(5):1274-1283. doi: 10.3892/ijo.2020.4993. Epub 2020 Feb 19. Int J Oncol. 2020. PMID: 32319553

7

Dual nicotinamide phosphoribosyltransferase and epidermal growth factor receptor inhibitors for the treatment of cancer.

Zhang W, Zhang K, Yao Y, Liu Y, Ni Y, Liao C, Tu Z, Qiu Y, Wang D, Chen D, Qiang L, Li Z, Jiang S. Zhang W, et al. Among authors: zhang k. Eur J Med Chem. 2021 Feb 5;211:113022. doi: 10.1016/j.ejmech.2020.113022. Epub 2020 Nov 13. Eur J Med Chem. 2021. PMID: 33239261

8

A new predictive biomarker enables more accurate PD-1 blockade therapy.

Zhang K, Jiang S. Zhang K, et al. Cell Mol Immunol. 2021 Jul;18(7):1624-1625. doi: 10.1038/s41423-021-00645-4. Epub 2021 Feb 8. Cell Mol Immunol. 2021. PMID: 33558685 Free PMC article. No abstract available.

9

Novel Biphenyl Pyridines as Potent Small-Molecule Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.

Wang T, Cai S, Wang M, Zhang W, Zhang K, Chen D, Li Z, Jiang S. Wang T, et al. Among authors: zhang w, zhang k. J Med Chem. 2021 Jun 10;64(11):7390-7403. doi: 10.1021/acs.jmedchem.1c00010. Epub 2021 May 30. J Med Chem. 2021. PMID: 34056906

10

Design, Synthesis, and Evaluation of PD-1/PD-L1 Antagonists Bearing a Benzamide Scaffold.

Lu L, Qi Z, Wang T, Zhang X, Zhang K, Wang K, Cheng Y, Xiao Y, Li Z, Jiang S. Lu L, et al. Among authors: zhang k, zhang x. ACS Med Chem Lett. 2022 Mar 29;13(4):586-592. doi: 10.1021/acsmedchemlett.1c00646. eCollection 2022 Apr 14. ACS Med Chem Lett. 2022. PMID: 35450381 Free PMC article.

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