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109 results

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Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis.
Taha-Mehlitz S, Bianco G, Coto-Llerena M, Kancherla V, Bantug GR, Gallon J, Ercan C, Panebianco F, Eppenberger-Castori S, von Strauss M, Staubli S, Bolli M, Peterli R, Matter MS, Terracciano LM, von Flüe M, Ng CKY, Soysal SD, Kollmar O, Piscuoglio S. Taha-Mehlitz S, et al. Among authors: ercan c. Theranostics. 2021 Feb 15;11(9):4011-4029. doi: 10.7150/thno.50051. eCollection 2021. Theranostics. 2021. PMID: 33754045 Free PMC article.
A Pygopus 2-Histone Interaction Is Critical for Cancer Cell Dedifferentiation and Progression in Malignant Breast Cancer.
Saxena M, Kalathur RKR, Rubinstein N, Vettiger A, Sugiyama N, Neutzner M, Coto-Llerena M, Kancherla V, Ercan C, Piscuoglio S, Fischer J, Fagiani E, Cantù C, Basler K, Christofori G. Saxena M, et al. Among authors: ercan c. Cancer Res. 2020 Sep 1;80(17):3631-3648. doi: 10.1158/0008-5472.CAN-19-2910. Epub 2020 Jun 25. Cancer Res. 2020. PMID: 32586983
Transcriptional Enhancer Factor Domain Family member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo-Independent Regulation of Heat Shock Protein 70 Family Members.
Coto-Llerena M, Tosti N, Taha-Mehlitz S, Kancherla V, Paradiso V, Gallon J, Bianco G, Garofoli A, Ghosh S, Tang F, Ercan C, Christofori GM, Matter MS, Droeser RA, Zavolan M, Soysal SD, von Flüe M, Kollmar O, Terracciano LM, Ng CKY, Piscuoglio S. Coto-Llerena M, et al. Among authors: ercan c. Hepatol Commun. 2021 Jan 20;5(4):661-674. doi: 10.1002/hep4.1656. eCollection 2021 Apr. Hepatol Commun. 2021. PMID: 33860124 Free PMC article.
mTOR signaling mediates ILC3-driven immunopathology.
Teufel C, Horvath E, Peter A, Ercan C, Piscuoglio S, Hall MN, Finke D, Lehmann FM. Teufel C, et al. Among authors: ercan c. Mucosal Immunol. 2021 Nov;14(6):1323-1334. doi: 10.1038/s41385-021-00432-4. Epub 2021 Aug 2. Mucosal Immunol. 2021. PMID: 34341503 Free PMC article.
High Density of CD16+ Tumor-Infiltrating Immune Cells in Recurrent Ovarian Cancer Is Associated with Enhanced Responsiveness to Chemotherapy and Prolonged Overall Survival.
Lalos A, Neri O, Ercan C, Wilhelm A, Staubli S, Posabella A, Weixler B, Terracciano L, Piscuoglio S, Stadlmann S, Spagnoli GC, Droeser RA, Singer G. Lalos A, et al. Among authors: ercan c. Cancers (Basel). 2021 Nov 18;13(22):5783. doi: 10.3390/cancers13225783. Cancers (Basel). 2021. PMID: 34830938 Free PMC article.
Supervised learning based on tumor imaging and biopsy transcriptomics predicts response of hepatocellular carcinoma to transarterial chemoembolization.
Boldanova T, Fucile G, Vosshenrich J, Suslov A, Ercan C, Coto-Llerena M, Terracciano LM, Zech CJ, Boll DT, Wieland S, Heim MH. Boldanova T, et al. Among authors: ercan c. Cell Rep Med. 2021 Nov 16;2(11):100444. doi: 10.1016/j.xcrm.2021.100444. eCollection 2021 Nov 16. Cell Rep Med. 2021. PMID: 34841291 Free PMC article.
Epigenetic priming in chronic liver disease impacts the transcriptional and genetic landscapes of hepatocellular carcinoma.
Gallon J, Coto-Llerena M, Ercan C, Bianco G, Paradiso V, Nuciforo S, Taha-Melitz S, Meier MA, Boldanova T, Pérez-Del-Pulgar S, Rodríguez-Tajes S, von Flüe M, Soysal SD, Kollmar O, Llovet JM, Villanueva A, Terracciano LM, Heim MH, Ng CKY, Piscuoglio S. Gallon J, et al. Among authors: ercan c. Mol Oncol. 2022 Feb;16(3):665-682. doi: 10.1002/1878-0261.13154. Epub 2021 Dec 29. Mol Oncol. 2022. PMID: 34863035 Free PMC article.
109 results