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Type I, II, and III interferon signatures correspond to COVID-19 disease severity.
Kim MH, Salloum S, Wang JY, Wong LP, Regan J, Lefteri K, Manickas-Hill Z; MGH COVID-19 Collection & Processing Team; Li JZ, Sadreyev RI, Yu XG, Chung RT. Kim MH, et al. Among authors: li jz. medRxiv [Preprint]. 2021 Mar 12:2021.03.10.21253317. doi: 10.1101/2021.03.10.21253317. medRxiv. 2021. PMID: 33758894 Free PMC article. Preprint.
Point-of-care testing for COVID-19 using SHERLOCK diagnostics.
Joung J, Ladha A, Saito M, Segel M, Bruneau R, Huang MW, Kim NG, Yu X, Li J, Walker BD, Greninger AL, Jerome KR, Gootenberg JS, Abudayyeh OO, Zhang F. Joung J, et al. medRxiv [Preprint]. 2020 May 8:2020.05.04.20091231. doi: 10.1101/2020.05.04.20091231. medRxiv. 2020. PMID: 32511521 Free PMC article. Preprint.
Profound Treg perturbations correlate with COVID-19 severity.
Galvan-Pena S, Leon J, Chowdhary K, Michelson DA, Vijaykumar B, Yang L, Magnuson A, Manickas-Hill Z, Piechocka-Trocha A, Worrall DP, Hall KE, Ghebremichael M, Walker BD, Li JZ, Yu XG, Mathis D, Benoist C. Galvan-Pena S, et al. Among authors: li jz. bioRxiv [Preprint]. 2020 Dec 15:2020.12.11.416180. doi: 10.1101/2020.12.11.416180. bioRxiv. 2020. Update in: Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2111315118. doi: 10.1073/pnas.2111315118 PMID: 33330871 Free PMC article. Updated. Preprint.
Expansion of Cytotoxic CD4+ T cells in the lungs in severe COVID-19.
Kaneko N, Boucau J, Kuo HH, Perugino C, Mahajan VS, Farmer JR, Liu H, Diefenbach TJ, Piechocka-Trocha A, Lefteri K, Waring MT, Premo KR, Walker BD, Li JZ, Gaiha G, Yu XG, Lichterfeld M, Padera RF, Pillai S. Kaneko N, et al. Among authors: li jz. medRxiv [Preprint]. 2021 Mar 26:2021.03.23.21253885. doi: 10.1101/2021.03.23.21253885. medRxiv. 2021. Update in: Clin Immunol. 2022 Apr;237:108991. doi: 10.1016/j.clim.2022.108991 PMID: 33791730 Free PMC article. Updated. Preprint.
Emergence of SARS-CoV-2 Resistance with Monoclonal Antibody Therapy.
Choudhary MC, Chew KW, Deo R, Flynn JP, Regan J, Crain CR, Moser C, Hughes M, Ritz J, Ribeiro RM, Ke R, Dragavon JA, Javan AC, Nirula A, Klekotka P, Greninger AL, Fletcher CV, Daar ES, Wohl DA, Eron JJ, Currier JS, Parikh UM, Sieg SF, Perelson AS, Coombs RW, Smith DM, Li JZ; ACTIV-2/A5401 Study Team. Choudhary MC, et al. Among authors: li jz. medRxiv [Preprint]. 2021 Sep 15:2021.09.03.21263105. doi: 10.1101/2021.09.03.21263105. medRxiv. 2021. PMID: 34545376 Free PMC article. Preprint.
Vaccine Breakthrough Infection with the SARS-CoV-2 Delta or Omicron (BA.1) Variant Leads to Distinct Profiles of Neutralizing Antibody Responses.
Seaman MS, Siedner MJ, Boucau J, Lavine CL, Ghantous F, Liew MY, Mathews J, Singh A, Marino C, Regan J, Uddin R, Choudhary MC, Flynn JP, Chen G, Stuckwisch AM, Lipiner T, Kittilson A, Melberg M, Gilbert RF, Reynolds Z, Iyer SL, Chamberlin GC, Vyas TD, Vyas JM, Goldberg MB, Luban J, Li JZ, Barczak AK, Lemieux JE. Seaman MS, et al. Among authors: li jz. medRxiv [Preprint]. 2022 Mar 3:2022.03.02.22271731. doi: 10.1101/2022.03.02.22271731. medRxiv. 2022. Update in: JCI Insight. 2022 Oct 10;7(19):e159944. doi: 10.1172/jci.insight.159944 PMID: 35262094 Free PMC article. Updated. Preprint.
SARS-CoV-2 Viral Clearance and Evolution Varies by Extent of Immunodeficiency.
Li Y, Choudhary MC, Regan J, Boucau J, Nathan A, Speidel T, Liew MY, Edelstein GE, Kawano Y, Uddin R, Deo R, Marino C, Getz MA, Reynold Z, Barry M, Gilbert RF, Tien D, Sagar S, Vyas TD, Flynn JP, Hammond SP, Novack LA, Choi B, Cernadas M, Wallace ZS, Sparks JA, Vyas JM, Seaman MS, Gaiha GD, Siedner MJ, Barczak AK, Lemieux JE, Li JZ. Li Y, et al. Among authors: li jz. medRxiv [Preprint]. 2023 Aug 7:2023.07.31.23293441. doi: 10.1101/2023.07.31.23293441. medRxiv. 2023. Update in: Sci Transl Med. 2024 Jan 24;16(731):eadk1599. doi: 10.1126/scitranslmed.adk1599 PMID: 37577493 Free PMC article. Updated. Preprint.
SARS-CoV-2 infection elucidates unique features of pregnancy-specific immunity.
Oh DS, Kim E, Lu G, Normand R, Shook LL, Lyall A, Jasset O, Demidkin S, Gilbert E, Kim J, Akinwunmi B, Tantivit J, Tirard A, Arnold BY, Slowikowski K; MGH COVID-19 Collection & Processing Team; Goldberg MB, Filbin MR, Hacohen N, Nguyen LH, Chan AT, Yu XG, Li JZ, Yonker L, Fasano A, Perlis RH, Pasternak O, Gray KJ, Choi GB, Drew DA, Sen P, Villani AC, Edlow AG, Huh JR. Oh DS, et al. Among authors: li jz. medRxiv [Preprint]. 2024 Feb 7:2024.02.05.24301794. doi: 10.1101/2024.02.05.24301794. medRxiv. 2024. Update in: Cell Rep. 2024 Nov 26;43(11):114933. doi: 10.1016/j.celrep.2024.114933 PMID: 38370801 Free PMC article. Updated. Preprint.
Bamlanivimab reduces nasopharyngeal SARS-CoV-2 RNA levels but not symptom duration in non-hospitalized adults with COVID-19: A Phase 2 Randomized Clinical Trial.
Chew KW, Moser C, Daar ES, Wohl DA, Li JZ, Coombs R, Ritz J, Giganti M, Javan AC, Li Y, Malvestutto C, Klekotka P, Price K, Nirula A, Fischer W, Bala V, Ribeiro RM, Perelson AS, Fletcher CV, Eron JJ, Currier JS, Hughes MD, Smith DM; ACTIV-2/A5401 Study Team. Chew KW, et al. Among authors: li jz, li y. medRxiv [Preprint]. 2021 Dec 21:2021.12.17.21268009. doi: 10.1101/2021.12.17.21268009. medRxiv. 2021. PMID: 34981077 Free PMC article. Preprint.
1,116 results