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Type I, II, and III interferon signatures correspond to COVID-19 disease severity.
Kim MH, Salloum S, Wang JY, Wong LP, Regan J, Lefteri K, Manickas-Hill Z; MGH COVID-19 Collection & Processing Team; Li JZ, Sadreyev RI, Yu XG, Chung RT. Kim MH, et al. Among authors: regan j. medRxiv [Preprint]. 2021 Mar 12:2021.03.10.21253317. doi: 10.1101/2021.03.10.21253317. medRxiv. 2021. PMID: 33758894 Free PMC article. Preprint.
SARS-CoV-2 viral load is associated with increased disease severity and mortality.
Fajnzylber J, Regan J, Coxen K, Corry H, Wong C, Rosenthal A, Worrall D, Giguel F, Piechocka-Trocha A, Atyeo C, Fischinger S, Chan A, Flaherty KT, Hall K, Dougan M, Ryan ET, Gillespie E, Chishti R, Li Y, Jilg N, Hanidziar D, Baron RM, Baden L, Tsibris AM, Armstrong KA, Kuritzkes DR, Alter G, Walker BD, Yu X, Li JZ; Massachusetts Consortium for Pathogen Readiness. Fajnzylber J, et al. Among authors: regan j. Nat Commun. 2020 Oct 30;11(1):5493. doi: 10.1038/s41467-020-19057-5. Nat Commun. 2020. PMID: 33127906 Free PMC article.
Increased Prevalence of Myocardial Injury in Patients with SARS-CoV-2 Viremia.
Siddiqi HK, Weber B, Zhou G, Regan J, Fajnzylber J, Coxen K, Corry H, Yu XG, DiCarli M, Li JZ, Bhatt DL. Siddiqi HK, et al. Among authors: regan j. Am J Med. 2021 Apr;134(4):542-546. doi: 10.1016/j.amjmed.2020.09.046. Epub 2020 Nov 10. Am J Med. 2021. PMID: 33181107 Free PMC article.
SARS-CoV-2 Viremia is Associated with Distinct Proteomic Pathways and Predicts COVID-19 Outcomes.
Li Y, Schneider AM, Mehta A, Sade-Feldman M, Kays KR, Gentili M, Charland NC, Gonye ALK, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilly BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Parry BA, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Regan J, Flynn JP, Villani AC, Hacohen N, Goldberg MB, Filbin MR, Li JZ. Li Y, et al. Among authors: regan j. medRxiv [Preprint]. 2021 Feb 26:2021.02.24.21252357. doi: 10.1101/2021.02.24.21252357. medRxiv. 2021. Update in: J Clin Invest. 2021 Jul 1;131(13):148635. doi: 10.1172/JCI148635 PMID: 33655257 Free PMC article. Updated. Preprint.
Virologic features of SARS-CoV-2 infection in children.
Yonker LM, Boucau J, Regan J, Choudhary MC, Burns MD, Young N, Farkas EJ, Davis JP, Moschovis PP, Kinane TB, Fasano A, Neilan AM, Li JZ, Barczak AK. Yonker LM, et al. Among authors: regan j. medRxiv [Preprint]. 2021 Aug 17:2021.05.30.21258086. doi: 10.1101/2021.05.30.21258086. medRxiv. 2021. Update in: J Infect Dis. 2021 Dec 1;224(11):1821-1829. doi: 10.1093/infdis/jiab509 PMID: 34124714 Free PMC article. Updated. Preprint.
Emergence of SARS-CoV-2 Resistance with Monoclonal Antibody Therapy.
Choudhary MC, Chew KW, Deo R, Flynn JP, Regan J, Crain CR, Moser C, Hughes M, Ritz J, Ribeiro RM, Ke R, Dragavon JA, Javan AC, Nirula A, Klekotka P, Greninger AL, Fletcher CV, Daar ES, Wohl DA, Eron JJ, Currier JS, Parikh UM, Sieg SF, Perelson AS, Coombs RW, Smith DM, Li JZ; ACTIV-2/A5401 Study Team. Choudhary MC, et al. Among authors: regan j. medRxiv [Preprint]. 2021 Sep 15:2021.09.03.21263105. doi: 10.1101/2021.09.03.21263105. medRxiv. 2021. PMID: 34545376 Free PMC article. Preprint.
Liver Fibrosis Index FIB-4 Is Associated With Mortality in COVID-19.
Li Y, Regan J, Fajnzylber J, Coxen K, Corry H, Wong C, Rosenthal A, Atyeo C, Fischinger S, Gillespie E, Chishti R, Baden L, Yu XG, Alter G, Kim A, Li JZ. Li Y, et al. Among authors: regan j. Hepatol Commun. 2021 Mar;5(3):434-445. doi: 10.1002/hep4.1650. Epub 2020 Dec 10. Hepatol Commun. 2021. PMID: 34553511 Free PMC article.
Monoclonal antibody treatment drives rapid culture conversion in SARS-CoV-2 infection.
Boucau J, Chew KW, Choudhary M, Deo R, Regan J, Flynn JP, Crain CR, Hughes MD, Ritz J, Moser C, Dragavon JA, Javan AC, Nirula A, Klekotka P, Greninger AL, Coombs RW, Fischer WA 2nd, Daar ES, Wohl DA, Eron JJ, Currier JS, Smith DM, Li JZ, Barczak AK; ACTIV-2/A5401 Study Team. Boucau J, et al. Among authors: regan j. medRxiv [Preprint]. 2021 Dec 30:2021.12.25.21268211. doi: 10.1101/2021.12.25.21268211. medRxiv. 2021. Update in: Cell Rep Med. 2022 Jul 19;3(7):100678. doi: 10.1016/j.xcrm.2022.100678 PMID: 35018382 Free PMC article. Updated. Preprint.
Duration of viable virus shedding in SARS-CoV-2 omicron variant infection.
Boucau J, Marino C, Regan J, Uddin R, Choudhary MC, Flynn JP, Chen G, Stuckwisch AM, Mathews J, Liew MY, Singh A, Lipiner T, Kittilson A, Melberg M, Li Y, Gilbert RF, Reynolds Z, Iyer SL, Chamberlin GC, Vyas TD, Goldberg MB, Vyas JM, Li JZ, Lemieux JE, Siedner MJ, Barczak AK. Boucau J, et al. Among authors: regan j. medRxiv [Preprint]. 2022 Mar 2:2022.03.01.22271582. doi: 10.1101/2022.03.01.22271582. medRxiv. 2022. Update in: N Engl J Med. 2022 Jul 21;387(3):275-277. doi: 10.1056/NEJMc2202092 PMID: 35262089 Free PMC article. Updated. Preprint.
1,026 results