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Type I, II, and III interferon signatures correspond to COVID-19 disease severity.
Kim MH, Salloum S, Wang JY, Wong LP, Regan J, Lefteri K, Manickas-Hill Z; MGH COVID-19 Collection & Processing Team; Li JZ, Sadreyev RI, Yu XG, Chung RT. Kim MH, et al. Among authors: sadreyev ri. medRxiv [Preprint]. 2021 Mar 12:2021.03.10.21253317. doi: 10.1101/2021.03.10.21253317. medRxiv. 2021. PMID: 33758894 Free PMC article. Preprint.
The glutathione S-transferase Gstt1 drives survival and dissemination in metastases.
Ferrer CM, Cho HM, Boon R, Bernasocchi T, Wong LP, Cetinbas M, Haggerty ER, Mitsiades I, Wojtkiewicz GR, McLoughlin DE, Aboushousha R, Abdelhamid H, Kugel S, Rheinbay E, Sadreyev R, Juric D, Janssen-Heininger YMW, Mostoslavsky R. Ferrer CM, et al. Nat Cell Biol. 2024 Jun;26(6):975-990. doi: 10.1038/s41556-024-01426-7. Epub 2024 Jun 11. Nat Cell Biol. 2024. PMID: 38862786
Venous Endothelial Cell Transcriptomic Profiling Implicates METAP1 in Preeclampsia.
Pabon MA, Weisbrod RM, Castro C, Li H, Xia P, Kang J, Ardissino M, Economy KE, Yang Z, Shi Y, Kim E, Perillo A, Barrett L, Brown JM, Divakaran S, Cetinbas M, Sadreyev RI, de Marvao A, Wood MJ, Scott NS, Lau ES, Ho JE, Di Carli MF, Roh JD, Hamburg NM, Honigberg MC. Pabon MA, et al. Among authors: sadreyev ri. Circ Res. 2025 Jan 17;136(2):180-190. doi: 10.1161/CIRCRESAHA.124.324606. Epub 2024 Dec 27. Circ Res. 2025. PMID: 39727051 Free article.
Multi-omics approaches reveal that diffuse midline gliomas present altered DNA replication and are susceptible to replication stress therapy.
Hains AE, Chetal K, Nakatani T, Marques JG, Ettinger A, Junior CAOB, Gonzalez-Sandoval A, Pillai R, Filbin MG, Torres-Padilla ME, Sadreyev RI, Van Rechem C. Hains AE, et al. Among authors: sadreyev ri. Genome Biol. 2024 Dec 20;25(1):319. doi: 10.1186/s13059-024-03460-y. Genome Biol. 2024. PMID: 39707510 Free PMC article.
The restricted N-glycome of neurons is programmed during differentiation.
Kiwimagi K, Noel M, Cetinbas M, Sadreyev RI, Wang L, Smoller JW, Cummings RD, Weiss R, Mealer RG. Kiwimagi K, et al. Among authors: sadreyev ri. bioRxiv [Preprint]. 2024 Oct 17:2024.10.15.618477. doi: 10.1101/2024.10.15.618477. bioRxiv. 2024. PMID: 39463965 Free PMC article. Preprint.
An aging-sensitive compensatory secretory phospholipase that confers neuroprotection and cognitive resilience.
Vicidomini C, Goode TD, McAvoy KM, Yu R, Beveridge CH, Iyer SN, Victor MB, Leary N, Evans L, Steinbaugh MJ, Lai ZW, Lyon MC, Silvestre MRFS, Bonilla G, Sadreyev RI, Walther TC, Sui SH, Saido T, Yamamoto K, Murakami M, Tsai LH, Chopra G, Sahay A. Vicidomini C, et al. Among authors: sadreyev ri. bioRxiv [Preprint]. 2024 Sep 3:2024.07.26.605338. doi: 10.1101/2024.07.26.605338. bioRxiv. 2024. PMID: 39211220 Free PMC article. Preprint.
Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators.
Bonilla G, Morris A, Kundu S, DuCasse A, Kirkpatrick G, Jeffries NE, Chetal K, Yvanovich EE, Milosevic J, Zhao T, Xia J, Barghout R, Scadden D, Mansour MK, Kingston RE, Sykes DB, Mercier FE, Sadreyev RI. Bonilla G, et al. Among authors: sadreyev ri. bioRxiv [Preprint]. 2024 Nov 20:2024.02.29.582846. doi: 10.1101/2024.02.29.582846. bioRxiv. 2024. PMID: 38496490 Free PMC article. Preprint.
143 results