Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2.
Incio J, Ligibel JA, McManus DT, Suboj P, Jung K, Kawaguchi K, Pinter M, Babykutty S, Chin SM, Vardam TD, Huang Y, Rahbari NN, Roberge S, Wang D, Gomes-Santos IL, Puchner SB, Schlett CL, Hoffmman U, Ancukiewicz M, Tolaney SM, Krop IE, Duda DG, Boucher Y, Fukumura D, Jain RK.
Incio J, et al. Among authors: rahbari nn.
Sci Transl Med. 2018 Mar 14;10(432):eaag0945. doi: 10.1126/scitranslmed.aag0945.
Sci Transl Med. 2018.
PMID: 29540614
Free PMC article.