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Structure selectivity relationship studies of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-pyridyl)carboxamido]morphinan derivatives toward the development of the mu opioid receptor antagonists.
Yuan Y, Elbegdorj O, Chen J, Akubathini SK, Beletskaya IO, Selley DE, Zhang Y. Yuan Y, et al. Among authors: selley de. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5625-9. doi: 10.1016/j.bmcl.2011.06.135. Epub 2011 Jul 18. Bioorg Med Chem Lett. 2011. PMID: 21788135 Free PMC article.
Design, synthesis, and biological evaluation of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-pyridyl)carboxamido]morphinan derivatives as peripheral selective μ opioid receptor Agents.
Yuan Y, Elbegdorj O, Chen J, Akubathini SK, Zhang F, Stevens DL, Beletskaya IO, Scoggins KL, Zhang Z, Gerk PM, Selley DE, Akbarali HI, Dewey WL, Zhang Y. Yuan Y, et al. Among authors: selley de. J Med Chem. 2012 Nov 26;55(22):10118-29. doi: 10.1021/jm301247n. Epub 2012 Nov 9. J Med Chem. 2012. PMID: 23116124 Free PMC article.
Structure activity relationship studies of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan (NAQ) analogues as potent opioid receptor ligands: preliminary results on the role of electronic characteristics for affinity and function.
Yuan Y, Elbegdorj O, Beletskaya IO, Selley DE, Zhang Y. Yuan Y, et al. Among authors: selley de. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5045-8. doi: 10.1016/j.bmcl.2013.07.043. Epub 2013 Jul 31. Bioorg Med Chem Lett. 2013. PMID: 23948248 Free PMC article.
143 results