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Odontoblast TRPC5 channels signal cold pain in teeth.
Bernal L, Sotelo-Hitschfeld P, König C, Sinica V, Wyatt A, Winter Z, Hein A, Touska F, Reinhardt S, Tragl A, Kusuda R, Wartenberg P, Sclaroff A, Pfeifer JD, Ectors F, Dahl A, Freichel M, Vlachova V, Brauchi S, Roza C, Boehm U, Clapham DE, Lennerz JK, Zimmermann K. Bernal L, et al. Among authors: clapham de. Sci Adv. 2021 Mar 26;7(13):eabf5567. doi: 10.1126/sciadv.abf5567. Print 2021 Mar. Sci Adv. 2021. PMID: 33771873 Free PMC article.
TRPM7 facilitates cholinergic vesicle fusion with the plasma membrane.
Brauchi S, Krapivinsky G, Krapivinsky L, Clapham DE. Brauchi S, et al. Among authors: clapham de. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8304-8. doi: 10.1073/pnas.0800881105. Epub 2008 Jun 6. Proc Natl Acad Sci U S A. 2008. PMID: 18539771 Free PMC article.
Phenotyping sensory nerve endings in vitro in the mouse.
Zimmermann K, Hein A, Hager U, Kaczmarek JS, Turnquist BP, Clapham DE, Reeh PW. Zimmermann K, et al. Among authors: clapham de. Nat Protoc. 2009;4(2):174-96. doi: 10.1038/nprot.2008.223. Nat Protoc. 2009. PMID: 19180088 Free PMC article.
A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility.
Sheu SH, Upadhyayula S, Dupuy V, Pang S, Deng F, Wan J, Walpita D, Pasolli HA, Houser J, Sanchez-Martinez S, Brauchi SE, Banala S, Freeman M, Xu CS, Kirchhausen T, Hess HF, Lavis L, Li Y, Chaumont-Dubel S, Clapham DE. Sheu SH, et al. Among authors: clapham de. Cell. 2022 Sep 1;185(18):3390-3407.e18. doi: 10.1016/j.cell.2022.07.026. Cell. 2022. PMID: 36055200 Free PMC article.
Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function.
Duan J, Li J, Chen GL, Ge Y, Liu J, Xie K, Peng X, Zhou W, Zhong J, Zhang Y, Xu J, Xue C, Liang B, Zhu L, Liu W, Zhang C, Tian XL, Wang J, Clapham DE, Zeng B, Li Z, Zhang J. Duan J, et al. Among authors: clapham de. Sci Adv. 2019 Jul 24;5(7):eaaw7935. doi: 10.1126/sciadv.aaw7935. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31355338 Free PMC article.
283 results