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CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria.
Singh K, Cornell CS, Jackson R, Kabiri M, Phipps M, Desai M, Fogle R, Ying X, Anarat-Cappillino G, Geller S, Johnson J, Roberts E, Malley K, Devlin T, DeRiso M, Berthelette P, Zhang YV, Ryan S, Rao S, Thurberg BL, Bangari DS, Kyostio-Moore S. Singh K, et al. Sci Rep. 2021 Mar 31;11(1):7254. doi: 10.1038/s41598-021-86663-8. Sci Rep. 2021. PMID: 33790381 Free PMC article.
An experimental model of anti-PD-1 resistance exhibits activation of TGFß and Notch pathways and is sensitive to local mRNA immunotherapy.
Bernardo M, Tolstykh T, Zhang YA, Bangari DS, Cao H, Heyl KA, Lee JS, Malkova NV, Malley K, Marquez E, Pollard J, Qu H, Roberts E, Ryan S, Singh K, Sun F, Wang E, Bahjat K, Wiederschain D, Wagenaar TR. Bernardo M, et al. Among authors: singh k. Oncoimmunology. 2021 Mar 16;10(1):1881268. doi: 10.1080/2162402X.2021.1881268. Oncoimmunology. 2021. PMID: 33796402 Free PMC article.
The Novel Phosphate and Bile Acid Sequestrant Polymer SAR442357 Delays Disease Progression in a Rat Model of Diabetic Nephropathy.
Castañeda TR, Méndez M, Davison I, Elvert R, Schwahn U, Boldina G, Rocher C, Scherer P, Singh K, Bangari DS, Falkenhahn M, Kannt A, Konkar A, Larsen PJ, Arbeeny C, Dhal PK, Hübschle T. Castañeda TR, et al. Among authors: singh k. J Pharmacol Exp Ther. 2021 Feb;376(2):190-203. doi: 10.1124/jpet.120.000285. Epub 2020 Nov 17. J Pharmacol Exp Ther. 2021. PMID: 33203659
Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models.
Hotz C, Wagenaar TR, Gieseke F, Bangari DS, Callahan M, Cao H, Diekmann J, Diken M, Grunwitz C, Hebert A, Hsu K, Bernardo M, Karikó K, Kreiter S, Kuhn AN, Levit M, Malkova N, Masciari S, Pollard J, Qu H, Ryan S, Selmi A, Schlereth J, Singh K, Sun F, Tillmann B, Tolstykh T, Weber W, Wicke L, Witzel S, Yu Q, Zhang YA, Zheng G, Lager J, Nabel GJ, Sahin U, Wiederschain D. Hotz C, et al. Among authors: singh k. Sci Transl Med. 2021 Sep 8;13(610):eabc7804. doi: 10.1126/scitranslmed.abc7804. Epub 2021 Sep 8. Sci Transl Med. 2021. PMID: 34516826
Maternal and child health services during COVID-19 in India: Highlighting the role of primary care physicians in maintaining continuum of care.
Sharma S, Aggarwal S, Singh KJK, Singh L, Gaym A, Sahu D, Adhikari T, Nair S, Kumar A, Juneja A, Rao MVV. Sharma S, et al. Among authors: singh kjk. J Family Med Prim Care. 2024 Nov;13(11):5256-5264. doi: 10.4103/jfmpc.jfmpc_203_23. Epub 2024 Nov 18. J Family Med Prim Care. 2024. PMID: 39722985 Free PMC article.
Obesity modulates NK-cell activity via LDL & DUSP1 signaling for Populations with Adverse Social Determinants.
Baumer Y, Singh K, Saurabh A, Baez AS, Gutierrez-Huerta CA, Chen L, Igboko M, Turner BS, Yeboah JA, Reger RN, Ortiz-Whittingham LR, Joshi S, Andrews MR, Aquino Peterson EM, Bleck CK, Mendelsohn LG, Mitchell VM, Collins BS, Redekar NR, Kuhn SA, Combs CA, Pirooznia M, Dagur PK, Allan DS, Muallem-Schwartz D, Childs RW, Powell-Wiley TM. Baumer Y, et al. Among authors: singh k. JCI Insight. 2024 Dec 24:e180606. doi: 10.1172/jci.insight.180606. Online ahead of print. JCI Insight. 2024. PMID: 39718832 Free article.
9,939 results