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Stability of Outer Membrane Vesicles-Based Vaccines, Identifying the Most Appropriate Methods to Detect Changes in Vaccine Potency.
Palmieri E, Arato V, Oldrini D, Ricchetti B, Aruta MG, Pansegrau W, Marchi S, Giusti F, Ferlenghi I, Rossi O, Alfini R, Giannelli C, Gasperini G, Necchi F, Micoli F. Palmieri E, et al. Among authors: pansegrau w. Vaccines (Basel). 2021 Mar 6;9(3):229. doi: 10.3390/vaccines9030229. Vaccines (Basel). 2021. PMID: 33800727 Free PMC article.
A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells.
Bagnoli F, Moschioni M, Donati C, Dimitrovska V, Ferlenghi I, Facciotti C, Muzzi A, Giusti F, Emolo C, Sinisi A, Hilleringmann M, Pansegrau W, Censini S, Rappuoli R, Covacci A, Masignani V, Barocchi MA. Bagnoli F, et al. Among authors: pansegrau w. J Bacteriol. 2008 Aug;190(15):5480-92. doi: 10.1128/JB.00384-08. Epub 2008 May 30. J Bacteriol. 2008. PMID: 18515415 Free PMC article.
Human protective response induced by meningococcus B vaccine is mediated by the synergy of multiple bactericidal epitopes.
Giuliani M, Bartolini E, Galli B, Santini L, Lo Surdo P, Buricchi F, Bruttini M, Benucci B, Pacchiani N, Alleri L, Donnarumma D, Pansegrau W, Peschiera I, Ferlenghi I, Cozzi R, Norais N, Giuliani MM, Maione D, Pizza M, Rappuoli R, Finco O, Masignani V. Giuliani M, et al. Among authors: pansegrau w. Sci Rep. 2018 Feb 27;8(1):3700. doi: 10.1038/s41598-018-22057-7. Sci Rep. 2018. PMID: 29487324 Free PMC article.
The two variants of the Streptococcus pneumoniae pilus 1 RrgA adhesin retain the same function and elicit cross-protection in vivo.
Moschioni M, Emolo C, Biagini M, Maccari S, Pansegrau W, Donati C, Hilleringmann M, Ferlenghi I, Ruggiero P, Sinisi A, Pizza M, Norais N, Barocchi MA, Masignani V. Moschioni M, et al. Among authors: pansegrau w. Infect Immun. 2010 Dec;78(12):5033-42. doi: 10.1128/IAI.00601-10. Epub 2010 Sep 7. Infect Immun. 2010. PMID: 20823200 Free PMC article.
Structural and functional characterization of the Streptococcus pneumoniae RrgB pilus backbone D1 domain.
Gentile MA, Melchiorre S, Emolo C, Moschioni M, Gianfaldoni C, Pancotto L, Ferlenghi I, Scarselli M, Pansegrau W, Veggi D, Merola M, Cantini F, Ruggiero P, Banci L, Masignani V. Gentile MA, et al. Among authors: pansegrau w. J Biol Chem. 2011 Apr 22;286(16):14588-97. doi: 10.1074/jbc.M110.202739. Epub 2011 Mar 2. J Biol Chem. 2011. PMID: 21367860 Free PMC article.
Protective efficacy induced by recombinant Clostridium difficile toxin fragments.
Leuzzi R, Spencer J, Buckley A, Brettoni C, Martinelli M, Tulli L, Marchi S, Luzzi E, Irvine J, Candlish D, Veggi D, Pansegrau W, Fiaschi L, Savino S, Swennen E, Cakici O, Oviedo-Orta E, Giraldi M, Baudner B, D'Urzo N, Maione D, Soriani M, Rappuoli R, Pizza M, Douce GR, Scarselli M. Leuzzi R, et al. Among authors: pansegrau w. Infect Immun. 2013 Aug;81(8):2851-60. doi: 10.1128/IAI.01341-12. Epub 2013 May 28. Infect Immun. 2013. PMID: 23716610 Free PMC article.
Structural characterization of a cross-protective natural chimera of factor H binding protein from meningococcal serogroup B strain NL096.
Veggi D, Malito E, Lo Surdo P, Pansegrau W, Rippa V, Wahome N, Savino S, Masignani V, Pizza M, Bottomley MJ. Veggi D, et al. Among authors: pansegrau w. Comput Struct Biotechnol J. 2022 Apr 18;20:2070-2081. doi: 10.1016/j.csbj.2022.04.011. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35601959 Free PMC article.
4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp.
Veggi D, Bianchi F, Santini L, Lo Surdo P, Chesterman CC, Pansegrau W, Bechi N, Huang Y, Masignani V, Pizza M, Rappuoli R, Bottomley MJ, Cozzi R, Maione D. Veggi D, et al. Among authors: pansegrau w. PLoS Pathog. 2020 Oct 2;16(10):e1008882. doi: 10.1371/journal.ppat.1008882. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33007046 Free PMC article.
55 results