Horlock D - Search Results

1

Old Drug, New Trick: Tilorone, a Broad-Spectrum Antiviral Drug as a Potential Anti-Fibrotic Therapeutic for the Diseased Heart.

Horlock D, Kaye DM, Winbanks CE, Gao XM, Kiriazis H, Donner DG, Gregorevic P, McMullen JR, Bernardo BC. Horlock D, et al. Pharmaceuticals (Basel). 2021 Mar 15;14(3):263. doi: 10.3390/ph14030263. Pharmaceuticals (Basel). 2021. PMID: 33804032 Free PMC article.

2

CXCR4 Antagonism Reduces Cardiac Fibrosis and Improves Cardiac Performance in Dilated Cardiomyopathy.

Chu PY, Joshi MS, Horlock D, Kiriazis H, Kaye DM. Chu PY, et al. Among authors: horlock d. Front Pharmacol. 2019 Feb 19;10:117. doi: 10.3389/fphar.2019.00117. eCollection 2019. Front Pharmacol. 2019. PMID: 30837882 Free PMC article.

3

Abnormal mitochondrial L-arginine transport contributes to the pathogenesis of heart failure and rexoygenation injury.

Williams D, Venardos KM, Byrne M, Joshi M, Horlock D, Lam NT, Gregorevic P, McGee SL, Kaye DM. Williams D, et al. Among authors: horlock d. PLoS One. 2014 Aug 11;9(8):e104643. doi: 10.1371/journal.pone.0104643. eCollection 2014. PLoS One. 2014. PMID: 25111602 Free PMC article.

4

N-acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure.

Giam B, Chu PY, Kuruppu S, Smith AI, Horlock D, Kiriazis H, Du XJ, Kaye DM, Rajapakse NW. Giam B, et al. Among authors: horlock d. Physiol Rep. 2016 Apr;4(7):e12757. doi: 10.14814/phy2.12757. Epub 2016 Apr 13. Physiol Rep. 2016. PMID: 27081162 Free PMC article.

5

N-Acetylcysteine Attenuates the Development of Renal Fibrosis in Transgenic Mice with Dilated Cardiomyopathy.

Giam B, Kuruppu S, Chu PY, Smith AI, Marques FZ, Fiedler A, Horlock D, Kiriazis H, Du XJ, Kaye DM, Rajapakse NW. Giam B, et al. Among authors: horlock d. Sci Rep. 2017 Dec 18;7(1):17718. doi: 10.1038/s41598-017-17927-5. Sci Rep. 2017. PMID: 29255249 Free PMC article.

6

Serelaxin attenuates renal inflammation and fibrosis in a mouse model of dilated cardiomyopathy.

Giam B, Chu PY, Kuruppu S, Smith AI, Horlock D, Murali A, Kiriazis H, Du XJ, Kaye DM, Rajapakse NW. Giam B, et al. Among authors: horlock d. Exp Physiol. 2018 Dec;103(12):1593-1602. doi: 10.1113/EP087189. Epub 2018 Nov 5. Exp Physiol. 2018. PMID: 30311699 Free article.

7

Cardioprotective Actions of the Annexin-A1 N-Terminal Peptide, Ac_2-26, Against Myocardial Infarction.

Qin CX, Rosli S, Deo M, Cao N, Walsh J, Tate M, Alexander AE, Donner D, Horlock D, Li R, Kiriazis H, Lee MKS, Bourke JE, Yang Y, Murphy AJ, Du XJ, Gao XM, Ritchie RH. Qin CX, et al. Among authors: horlock d. Front Pharmacol. 2019 Apr 3;10:269. doi: 10.3389/fphar.2019.00269. eCollection 2019. Front Pharmacol. 2019. PMID: 31001111 Free PMC article.

8

Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease.

Kaye DM, Shihata WA, Jama HA, Tsyganov K, Ziemann M, Kiriazis H, Horlock D, Vijay A, Giam B, Vinh A, Johnson C, Fiedler A, Donner D, Snelson M, Coughlan MT, Phillips S, Du XJ, El-Osta A, Drummond G, Lambert GW, Spector TD, Valdes AM, Mackay CR, Marques FZ. Kaye DM, et al. Among authors: horlock d. Circulation. 2020 Apr 28;141(17):1393-1403. doi: 10.1161/CIRCULATIONAHA.119.043081. Epub 2020 Feb 25. Circulation. 2020. PMID: 32093510

9

Manipulation of the gut microbiota by the use of prebiotic fibre does not override a genetic predisposition to heart failure.

Jama HA, Fiedler A, Tsyganov K, Nelson E, Horlock D, Nakai ME, Kiriazis H, Johnson C, Du XJ, Mackay CR, Marques FZ, Kaye DM. Jama HA, et al. Among authors: horlock d. Sci Rep. 2020 Oct 21;10(1):17919. doi: 10.1038/s41598-020-73614-y. Sci Rep. 2020. PMID: 33087738 Free PMC article.

10

CXCR4 Antagonism Attenuates the Development of Diabetic Cardiac Fibrosis.

Chu PY, Walder K, Horlock D, Williams D, Nelson E, Byrne M, Jandeleit-Dahm K, Zimmet P, Kaye DM. Chu PY, et al. Among authors: horlock d. PLoS One. 2015 Jul 27;10(7):e0133616. doi: 10.1371/journal.pone.0133616. eCollection 2015. PLoS One. 2015. PMID: 26214690 Free PMC article.

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