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Page 1
FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition.
Reilly SM, Abu-Odeh M, Ameka M, DeLuca JH, Naber MC, Dadpey B, Ebadat N, Gomez AV, Peng X, Poirier B, Walk E, Potthoff MJ, Saltiel AR. Reilly SM, et al. Among authors: deluca jh. J Clin Invest. 2021 May 17;131(10):e145546. doi: 10.1172/JCI145546. J Clin Invest. 2021. PMID: 33822771 Free PMC article.
Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3.
Reilly SM, Hung CW, Ahmadian M, Zhao P, Keinan O, Gomez AV, DeLuca JH, Dadpey B, Lu D, Zaid J, Poirier B, Peng X, Yu RT, Downes M, Liddle C, Evans RM, Murphy AN, Saltiel AR. Reilly SM, et al. Among authors: deluca jh. Nat Metab. 2020 Jul;2(7):620-634. doi: 10.1038/s42255-020-0217-6. Epub 2020 Jun 8. Nat Metab. 2020. PMID: 32694788 Free PMC article.
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes.
Keinan O, Valentine JM, Xiao H, Mahata SK, Reilly SM, Abu-Odeh M, Deluca JH, Dadpey B, Cho L, Pan A, Yu RT, Dai Y, Liddle C, Downes M, Evans RM, Lusis AJ, Laakso M, Chouchani ET, Rydén M, Saltiel AR. Keinan O, et al. Among authors: deluca jh. Nature. 2021 Nov;599(7884):296-301. doi: 10.1038/s41586-021-04019-8. Epub 2021 Oct 27. Nature. 2021. PMID: 34707293 Free PMC article.
Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling.
Luan D, Dadpey B, Zaid J, Bridge-Comer PE, DeLuca JH, Xia W, Castle J, Reilly SM. Luan D, et al. Among authors: deluca jh. Diabetes. 2023 Mar 1;72(3):367-374. doi: 10.2337/db22-0444. Diabetes. 2023. PMID: 36449000 Free PMC article.