Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance.
Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky JM, Saltiel AR, Downes M, Evans RM.
Fang S, et al. Among authors: saltiel ar.
Nat Med. 2015 Feb;21(2):159-65. doi: 10.1038/nm.3760. Epub 2015 Jan 5.
Nat Med. 2015.
PMID: 25559344
Free PMC article.