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Life-extended glycosylated IL-2 promotes Treg induction and suppression of autoimmunity.
Ottolenghi A, Bolel P, Sarkar R, Greenshpan Y, Iraqi M, Ghosh S, Bhattacharya B, Taylor ZV, Kundu K, Radinsky O, Gazit R, Stepensky D, Apte RN, Voronov E, Porgador A. Ottolenghi A, et al. Among authors: voronov e. Sci Rep. 2021 Apr 7;11(1):7676. doi: 10.1038/s41598-021-87102-4. Sci Rep. 2021. PMID: 33828163 Free PMC article.
Opposing effects of IL-1 alpha and IL-1 beta on malignancy patterns. Tumor cell-associated IL-1 alpha potentiates anti-tumor immune responses and tumor regression, whereas IL-1 beta potentiates invasiveness.
Apte RN, Dvorkin T, Song X, Fima E, Krelin Y, Yulevitch A, Gurfinkel R, Werman A, White RM, Argov S, Shendler Y, Bjorkdahl O, Dohlsten M, Zoller M, Segal S, Voronov E. Apte RN, et al. Among authors: voronov e. Adv Exp Med Biol. 2000;479:277-88. Adv Exp Med Biol. 2000. PMID: 10897428 Review. No abstract available.
IL-1 is required for tumor invasiveness and angiogenesis.
Voronov E, Shouval DS, Krelin Y, Cagnano E, Benharroch D, Iwakura Y, Dinarello CA, Apte RN. Voronov E, et al. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2645-50. doi: 10.1073/pnas.0437939100. Epub 2003 Feb 21. Proc Natl Acad Sci U S A. 2003. PMID: 12598651 Free PMC article.
73 results