Sayers TJ - Search Results

1

Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins.

Tewary P, Brooks AD, Xu YM, Wijeratne EMK, Babyak AL, Back TC, Chari R, Evans CN, Henrich CJ, Meyer TJ, Edmondson EF, de Aquino MTP, Kanagasabai T, Shanker A, Gunatilaka AAL, Sayers TJ. Tewary P, et al. Among authors: sayers tj. Cancer Res. 2021 Jun 15;81(12):3374-3386. doi: 10.1158/0008-5472.CAN-20-2634. Epub 2021 Apr 9. Cancer Res. 2021. PMID: 33837043 Free PMC article.

2

Antigen presented by tumors in vivo determines the nature of CD8+ T-cell cytotoxicity.

Shanker A, Brooks AD, Jacobsen KM, Wine JW, Wiltrout RH, Yagita H, Sayers TJ. Shanker A, et al. Among authors: sayers tj. Cancer Res. 2009 Aug 15;69(16):6615-23. doi: 10.1158/0008-5472.CAN-09-0685. Epub 2009 Aug 4. Cancer Res. 2009. PMID: 19654302 Free PMC article.

3

Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity.

Shanker A, Pellom ST Jr, Dudimah DF, Thounaojam MC, de Kluyver RL, Brooks AD, Yagita H, McVicar DW, Murphy WJ, Longo DL, Sayers TJ. Shanker A, et al. Among authors: sayers tj. Cancer Res. 2015 Dec 15;75(24):5260-72. doi: 10.1158/0008-5472.CAN-15-0794. Epub 2015 Oct 22. Cancer Res. 2015. PMID: 26494122 Free PMC article.

4

Using natural products to promote caspase-8-dependent cancer cell death.

Tewary P, Gunatilaka AA, Sayers TJ. Tewary P, et al. Among authors: sayers tj. Cancer Immunol Immunother. 2017 Feb;66(2):223-231. doi: 10.1007/s00262-016-1855-0. Epub 2016 Jun 10. Cancer Immunol Immunother. 2017. PMID: 27286684 Free PMC article. Review.

5

17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor-α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure-Activity Relationships.

Xu YM, Brooks AD, Wijeratne EM, Henrich CJ, Tewary P, Sayers TJ, Gunatilaka AA. Xu YM, et al. Among authors: sayers tj. J Med Chem. 2017 Apr 13;60(7):3039-3051. doi: 10.1021/acs.jmedchem.7b00069. Epub 2017 Mar 21. J Med Chem. 2017. PMID: 28257574 Free PMC article.

6

Ring A/B-Modified 17β-Hydroxywithanolide Analogues as Antiproliferative Agents for Prostate Cancer and Potentiators of Immunotherapy for Renal Carcinoma and Melanoma.

Kithsiri Wijeratne EM, Xu YM, Liu MX, Inacio MC, Brooks AD, Tewary P, Sayers TJ, Gunatilaka AAL. Kithsiri Wijeratne EM, et al. Among authors: sayers tj. J Nat Prod. 2021 Dec 24;84(12):3029-3038. doi: 10.1021/acs.jnatprod.1c00724. Epub 2021 Dec 1. J Nat Prod. 2021. PMID: 34851111

7

Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody.

Shanker A, Brooks AD, Tristan CA, Wine JW, Elliott PJ, Yagita H, Takeda K, Smyth MJ, Murphy WJ, Sayers TJ. Shanker A, et al. Among authors: sayers tj. J Natl Cancer Inst. 2008 May 7;100(9):649-62. doi: 10.1093/jnci/djn113. Epub 2008 Apr 29. J Natl Cancer Inst. 2008. PMID: 18445820 Free PMC article.

8

Sensitizing tumor cells to immune-mediated cytotoxicity.

Shanker A, Sayers T. Shanker A, et al. Adv Exp Med Biol. 2007;601:163-71. doi: 10.1007/978-0-387-72005-0_17. Adv Exp Med Biol. 2007. PMID: 17713003 Review.

9

Tumor-specific CTL kill murine renal cancer cells using both perforin and Fas ligand-mediated lysis in vitro, but cause tumor regression in vivo in the absence of perforin.

Seki N, Brooks AD, Carter CR, Back TC, Parsoneault EM, Smyth MJ, Wiltrout RH, Sayers TJ. Seki N, et al. Among authors: sayers tj. J Immunol. 2002 Apr 1;168(7):3484-92. doi: 10.4049/jimmunol.168.7.3484. J Immunol. 2002. PMID: 11907109

10

Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer.

Seki N, Hayakawa Y, Brooks AD, Wine J, Wiltrout RH, Yagita H, Tanner JE, Smyth MJ, Sayers TJ. Seki N, et al. Among authors: sayers tj. Cancer Res. 2003 Jan 1;63(1):207-13. Cancer Res. 2003. PMID: 12517799

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