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201 results

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Symptom-level modelling unravels the shared genetic architecture of anxiety and depression.
Thorp JG, Campos AI, Grotzinger AD, Gerring ZF, An J, Ong JS, Wang W; 23andMe Research Team; Shringarpure S, Byrne EM, MacGregor S, Martin NG, Medland SE, Middeldorp CM, Derks EM. Thorp JG, et al. Among authors: middeldorp cm. Nat Hum Behav. 2021 Oct;5(10):1432-1442. doi: 10.1038/s41562-021-01094-9. Epub 2021 Apr 15. Nat Hum Behav. 2021. PMID: 33859377
A whole genome association study of neuroticism using DNA pooling.
Shifman S, Bhomra A, Smiley S, Wray NR, James MR, Martin NG, Hettema JM, An SS, Neale MC, van den Oord EJ, Kendler KS, Chen X, Boomsma DI, Middeldorp CM, Hottenga JJ, Slagboom PE, Flint J. Shifman S, et al. Among authors: middeldorp cm. Mol Psychiatry. 2008 Mar;13(3):302-12. doi: 10.1038/sj.mp.4002048. Epub 2007 Jul 31. Mol Psychiatry. 2008. PMID: 17667963 Free PMC article.
Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands.
Wray NR, Middeldorp CM, Birley AJ, Gordon SD, Sullivan PF, Visscher PM, Nyholt DR, Willemsen G, de Geus EJ, Slagboom PE, Montgomery GW, Martin NG, Boomsma DI. Wray NR, et al. Among authors: middeldorp cm. Arch Gen Psychiatry. 2008 Jun;65(6):649-58. doi: 10.1001/archpsyc.65.6.649. Arch Gen Psychiatry. 2008. PMID: 18519823 Free PMC article.
Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression.
Middeldorp CM, Sullivan PF, Wray NR, Hottenga JJ, de Geus EJ, van den Berg M, Montgomery GW, Coventry WL, Statham DJ, Andrews G, Slagboom PE, Boomsma DI, Martin NG. Middeldorp CM, et al. Am J Med Genet B Neuropsychiatr Genet. 2009 Apr 5;150B(3):352-8. doi: 10.1002/ajmg.b.30817. Am J Med Genet B Neuropsychiatr Genet. 2009. PMID: 18615541 Free PMC article.
Genetic risk profiles for depression and anxiety in adult and elderly cohorts.
Demirkan A, Penninx BW, Hek K, Wray NR, Amin N, Aulchenko YS, van Dyck R, de Geus EJ, Hofman A, Uitterlinden AG, Hottenga JJ, Nolen WA, Oostra BA, Sullivan PF, Willemsen G, Zitman FG, Tiemeier H, Janssens AC, Boomsma DI, van Duijn CM, Middeldorp CM. Demirkan A, et al. Among authors: middeldorp cm. Mol Psychiatry. 2011 Jul;16(7):773-83. doi: 10.1038/mp.2010.65. Epub 2010 Jun 22. Mol Psychiatry. 2011. PMID: 20567237 Free PMC article.
Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?
Middeldorp CM, Slof-Op 't Landt MC, Medland SE, van Beijsterveldt CE, Bartels M, Willemsen G, Hottenga JJ, de Geus EJ, Suchiman HE, Dolan CV, Neale MC, Slagboom PE, Boomsma DI. Middeldorp CM, et al. Genes Brain Behav. 2010 Oct;9(7):808-16. doi: 10.1111/j.1601-183X.2010.00619.x. Epub 2010 Aug 12. Genes Brain Behav. 2010. PMID: 20633049 Free PMC article.
Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned.
Wray NR, Pergadia ML, Blackwood DH, Penninx BW, Gordon SD, Nyholt DR, Ripke S, MacIntyre DJ, McGhee KA, Maclean AW, Smit JH, Hottenga JJ, Willemsen G, Middeldorp CM, de Geus EJ, Lewis CM, McGuffin P, Hickie IB, van den Oord EJ, Liu JZ, Macgregor S, McEvoy BP, Byrne EM, Medland SE, Statham DJ, Henders AK, Heath AC, Montgomery GW, Martin NG, Boomsma DI, Madden PA, Sullivan PF. Wray NR, et al. Among authors: middeldorp cm. Mol Psychiatry. 2012 Jan;17(1):36-48. doi: 10.1038/mp.2010.109. Epub 2010 Nov 2. Mol Psychiatry. 2012. PMID: 21042317 Free PMC article.
201 results