Ekiert D - Search Results

1

Design of multi-scale protein complexes by hierarchical building block fusion.

Hsia Y, Mout R, Sheffler W, Edman NI, Vulovic I, Park YJ, Redler RL, Bick MJ, Bera AK, Courbet A, Kang A, Brunette TJ, Nattermann U, Tsai E, Saleem A, Chow CM, Ekiert D, Bhabha G, Veesler D, Baker D. Hsia Y, et al. Among authors: ekiert d. Nat Commun. 2021 Apr 16;12(1):2294. doi: 10.1038/s41467-021-22276-z. Nat Commun. 2021. PMID: 33863889 Free PMC article.

2

A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.

Bhabha G, Lee J, Ekiert DC, Gam J, Wilson IA, Dyson HJ, Benkovic SJ, Wright PE. Bhabha G, et al. Science. 2011 Apr 8;332(6026):234-8. doi: 10.1126/science.1198542. Science. 2011. PMID: 21474759 Free PMC article.

3

Computational design of proteins targeting the conserved stem region of influenza hemagglutinin.

Fleishman SJ, Whitehead TA, Ekiert DC, Dreyfus C, Corn JE, Strauch EM, Wilson IA, Baker D. Fleishman SJ, et al. Among authors: ekiert dc. Science. 2011 May 13;332(6031):816-21. doi: 10.1126/science.1202617. Science. 2011. PMID: 21566186 Free PMC article.

4

Cross-neutralization of influenza A viruses mediated by a single antibody loop.

Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, Lerner RA, Bhatt RR, Wilson IA. Ekiert DC, et al. Nature. 2012 Sep 27;489(7417):526-32. doi: 10.1038/nature11414. Epub 2012 Sep 16. Nature. 2012. PMID: 22982990 Free PMC article.

5

Divergent evolution of protein conformational dynamics in dihydrofolate reductase.

Bhabha G, Ekiert DC, Jennewein M, Zmasek CM, Tuttle LM, Kroon G, Dyson HJ, Godzik A, Wilson IA, Wright PE. Bhabha G, et al. Nat Struct Mol Biol. 2013 Nov;20(11):1243-9. doi: 10.1038/nsmb.2676. Epub 2013 Sep 29. Nat Struct Mol Biol. 2013. PMID: 24077226 Free PMC article.

6

Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts.

Liu Y, Tan YL, Zhang X, Bhabha G, Ekiert DC, Genereux JC, Cho Y, Kipnis Y, Bjelic S, Baker D, Kelly JW. Liu Y, et al. Among authors: ekiert dc. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4449-54. doi: 10.1073/pnas.1323268111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591605 Free PMC article.

7

De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.

Liu Y, Zhang X, Tan YL, Bhabha G, Ekiert DC, Kipnis Y, Bjelic S, Baker D, Kelly JW. Liu Y, et al. Among authors: ekiert dc. J Am Chem Soc. 2014 Sep 24;136(38):13102-5. doi: 10.1021/ja5056356. Epub 2014 Sep 11. J Am Chem Soc. 2014. PMID: 25209927 Free PMC article.

8

Exploring the repeat protein universe through computational protein design.

Brunette TJ, Parmeggiani F, Huang PS, Bhabha G, Ekiert DC, Tsutakawa SE, Hura GL, Tainer JA, Baker D. Brunette TJ, et al. Among authors: ekiert dc. Nature. 2015 Dec 24;528(7583):580-4. doi: 10.1038/nature16162. Epub 2015 Dec 16. Nature. 2015. PMID: 26675729 Free PMC article.

9

Architectures of Lipid Transport Systems for the Bacterial Outer Membrane.

Ekiert DC, Bhabha G, Isom GL, Greenan G, Ovchinnikov S, Henderson IR, Cox JS, Vale RD. Ekiert DC, et al. Cell. 2017 Apr 6;169(2):273-285.e17. doi: 10.1016/j.cell.2017.03.019. Cell. 2017. PMID: 28388411 Free PMC article.

10

LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.

Isom GL, Coudray N, MacRae MR, McManus CT, Ekiert DC, Bhabha G. Isom GL, et al. Cell. 2020 Apr 30;181(3):653-664.e19. doi: 10.1016/j.cell.2020.03.030. Cell. 2020. PMID: 32359438 Free PMC article.

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