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CryoET structures of immature HIV Gag reveal six-helix bundle.
Mendonça L, Sun D, Ning J, Liu J, Kotecha A, Olek M, Frosio T, Fu X, Himes BA, Kleinpeter AB, Freed EO, Zhou J, Aiken C, Zhang P. Mendonça L, et al. Among authors: kleinpeter ab. Commun Biol. 2021 Apr 16;4(1):481. doi: 10.1038/s42003-021-01999-1. Commun Biol. 2021. PMID: 33863979 Free PMC article.
How to package the RNA of HIV-1.
Kleinpeter A, Freed EO. Kleinpeter A, et al. Elife. 2020 Nov 17;9:e63585. doi: 10.7554/eLife.63585. Elife. 2020. PMID: 33200986 Free PMC article.
A stable immature lattice packages IP6 for HIV capsid maturation.
Mallery DL, Kleinpeter AB, Renner N, Faysal KMR, Novikova M, Kiss L, Wilson MSC, Ahsan B, Ke Z, Briggs JAG, Saiardi A, Böcking T, Freed EO, James LC. Mallery DL, et al. Among authors: kleinpeter ab. Sci Adv. 2021 Mar 10;7(11):eabe4716. doi: 10.1126/sciadv.abe4716. Print 2021 Mar. Sci Adv. 2021. PMID: 33692109 Free PMC article.
Structural basis of HIV-1 maturation inhibitor binding and activity.
Sarkar S, Zadrozny KK, Zadorozhnyi R, Russell RW, Quinn CM, Kleinpeter A, Ablan S, Meshkin H, Perilla JR, Freed EO, Ganser-Pornillos BK, Pornillos O, Gronenborn AM, Polenova T. Sarkar S, et al. Nat Commun. 2023 Mar 4;14(1):1237. doi: 10.1038/s41467-023-36569-y. Nat Commun. 2023. PMID: 36871077 Free PMC article.
Structural and Mechanistic Bases for Resistance of the M66I Capsid Variant to Lenacapavir.
Briganti L, Annamalai AS, Bester SM, Wei G, Andino-Moncada JR, Singh SP, Kleinpeter AB, Tripathi M, Nguyen B, Radhakrishnan R, Singh PK, Greenwood J, Schope LI, Haney R, Huang SW, Freed EO, Engelman AN, Francis AC, Kvaratskhelia M. Briganti L, et al. Among authors: kleinpeter ab. bioRxiv [Preprint]. 2024 Nov 25:2024.11.25.625199. doi: 10.1101/2024.11.25.625199. bioRxiv. 2024. PMID: 39651162 Free PMC article. Preprint.
14 results