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Page 1
Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation.
Said MA, Eldehna WM, Nocentini A, Fahim SH, Bonardi A, Elgazar AA, Kryštof V, Soliman DH, Abdel-Aziz HA, Gratteri P, Abou-Seri SM, Supuran CT. Said MA, et al. Among authors: fahim sh. Eur J Med Chem. 2020 Mar 1;189:112019. doi: 10.1016/j.ejmech.2019.112019. Epub 2020 Jan 2. Eur J Med Chem. 2020. PMID: 31972394
Probing benzenesulfonamide-thiazolidinone hybrids as multitarget directed ligands for efficient control of type 2 diabetes mellitus through targeting the enzymes: α-glucosidase and carbonic anhydrase II.
Gamal MA, Fahim SH, Giovannuzzi S, Fouad MA, Bonardi A, Gratteri P, Supuran CT, Hassan GS. Gamal MA, et al. Among authors: fahim sh. Eur J Med Chem. 2024 May 5;271:116434. doi: 10.1016/j.ejmech.2024.116434. Epub 2024 Apr 20. Eur J Med Chem. 2024. PMID: 38653067
Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IX.
Allam HA, Fahim SH, F Abo-Ashour M, Nocentini A, Elbakry ME, Abdelrahman MA, Eldehna WM, Ibrahim HS, Supuran CT. Allam HA, et al. Among authors: fahim sh. Eur J Med Chem. 2019 Oct 1;179:547-556. doi: 10.1016/j.ejmech.2019.06.081. Epub 2019 Jun 28. Eur J Med Chem. 2019. PMID: 31276899
Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors.
Said MA, Eldehna WM, Nocentini A, Bonardi A, Fahim SH, Bua S, Soliman DH, Abdel-Aziz HA, Gratteri P, Abou-Seri SM, Supuran CT. Said MA, et al. Among authors: fahim sh. Eur J Med Chem. 2020 Jan 1;185:111843. doi: 10.1016/j.ejmech.2019.111843. Epub 2019 Nov 2. Eur J Med Chem. 2020. PMID: 31718943
12 results