Lynch KW - Search Results

1

Alternative splicing redefines landscape of commonly mutated genes in acute myeloid leukemia.

Rivera OD, Mallory MJ, Quesnel-Vallières M, Chatrikhi R, Schultz DC, Carroll M, Barash Y, Cherry S, Lynch KW. Rivera OD, et al. Among authors: lynch kw. Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2014967118. doi: 10.1073/pnas.2014967118. Proc Natl Acad Sci U S A. 2021. PMID: 33876749 Free PMC article.

2

Signal- and development-dependent alternative splicing of LEF1 in T cells is controlled by CELF2.

Mallory MJ, Jackson J, Weber B, Chi A, Heyd F, Lynch KW. Mallory MJ, et al. Among authors: lynch kw. Mol Cell Biol. 2011 Jun;31(11):2184-95. doi: 10.1128/MCB.05170-11. Epub 2011 Mar 28. Mol Cell Biol. 2011. PMID: 21444716 Free PMC article.

3

A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs).

Motta-Mena LB, Smith SA, Mallory MJ, Jackson J, Wang J, Lynch KW. Motta-Mena LB, et al. Among authors: lynch kw. J Biol Chem. 2011 Jun 3;286(22):20043-53. doi: 10.1074/jbc.M111.218727. Epub 2011 Apr 20. J Biol Chem. 2011. PMID: 21507955 Free PMC article.

4

Control of alternative splicing in immune responses: many regulators, many predictions, much still to learn.

Martinez NM, Lynch KW. Martinez NM, et al. Among authors: lynch kw. Immunol Rev. 2013 May;253(1):216-36. doi: 10.1111/imr.12047. Immunol Rev. 2013. PMID: 23550649 Free PMC article. Review.

5

Transcriptome-wide RNA interaction profiling reveals physical and functional targets of hnRNP L in human T cells.

Shankarling G, Cole BS, Mallory MJ, Lynch KW. Shankarling G, et al. Among authors: lynch kw. Mol Cell Biol. 2014 Jan;34(1):71-83. doi: 10.1128/MCB.00740-13. Epub 2013 Oct 28. Mol Cell Biol. 2014. PMID: 24164894 Free PMC article.

6

Paralogs hnRNP L and hnRNP LL exhibit overlapping but distinct RNA binding constraints.

Smith SA, Ray D, Cook KB, Mallory MJ, Hughes TR, Lynch KW. Smith SA, et al. Among authors: lynch kw. PLoS One. 2013 Nov 11;8(11):e80701. doi: 10.1371/journal.pone.0080701. eCollection 2013. PLoS One. 2013. PMID: 24244709 Free PMC article.

7

In silico to in vivo splicing analysis using splicing code models.

Gazzara MR, Vaquero-Garcia J, Lynch KW, Barash Y. Gazzara MR, et al. Among authors: lynch kw. Methods. 2014 May 1;67(1):3-12. doi: 10.1016/j.ymeth.2013.11.006. Epub 2013 Dec 7. Methods. 2014. PMID: 24321485 Free PMC article.

8

An optogenetic gene expression system with rapid activation and deactivation kinetics.

Motta-Mena LB, Reade A, Mallory MJ, Glantz S, Weiner OD, Lynch KW, Gardner KH. Motta-Mena LB, et al. Among authors: lynch kw. Nat Chem Biol. 2014 Mar;10(3):196-202. doi: 10.1038/nchembio.1430. Epub 2014 Jan 12. Nat Chem Biol. 2014. PMID: 24413462 Free PMC article.

9

Stem-loop recognition by DDX17 facilitates miRNA processing and antiviral defense.

Moy RH, Cole BS, Yasunaga A, Gold B, Shankarling G, Varble A, Molleston JM, tenOever BR, Lynch KW, Cherry S. Moy RH, et al. Among authors: lynch kw. Cell. 2014 Aug 14;158(4):764-777. doi: 10.1016/j.cell.2014.06.023. Cell. 2014. PMID: 25126784 Free PMC article.

10

Thoughts on NGS, alternative splicing and what we still need to know.

Lynch KW. Lynch KW. RNA. 2015 Apr;21(4):683-4. doi: 10.1261/rna.050419.115. RNA. 2015. PMID: 25780190 Free PMC article. No abstract available.

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