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Page 1
Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ.
Della Chiara G, Gervasoni F, Fakiola M, Godano C, D'Oria C, Azzolin L, Bonnal RJP, Moreni G, Drufuca L, Rossetti G, Ranzani V, Bason R, De Simone M, Panariello F, Ferrari I, Fabbris T, Zanconato F, Forcato M, Romano O, Caroli J, Gruarin P, Sarnicola ML, Cordenonsi M, Bardelli A, Zucchini N, Ceretti AP, Mariani NM, Cassingena A, Sartore-Bianchi A, Testa G, Gianotti L, Opocher E, Pisati F, Tripodo C, Macino G, Siena S, Bicciato S, Piccolo S, Pagani M. Della Chiara G, et al. Among authors: tripodo c. Nat Commun. 2021 Apr 20;12(1):2340. doi: 10.1038/s41467-021-22544-y. Nat Commun. 2021. PMID: 33879786 Free PMC article.
Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome.
Aguado J, Sola-Carvajal A, Cancila V, Revêchon G, Ong PF, Jones-Weinert CW, Wallén Arzt E, Lattanzi G, Dreesen O, Tripodo C, Rossiello F, Eriksson M, d'Adda di Fagagna F. Aguado J, et al. Among authors: tripodo c. Nat Commun. 2019 Nov 18;10(1):4990. doi: 10.1038/s41467-019-13018-3. Nat Commun. 2019. PMID: 31740672 Free PMC article.
IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules.
Bisi S, Marchesi S, Rizvi A, Carra D, Beznoussenko GV, Ferrara I, Deflorian G, Mironov A, Bertalot G, Pisati F, Oldani A, Cattaneo A, Saberamoli G, Pece S, Viale G, Bachi A, Tripodo C, Scita G, Disanza A. Bisi S, et al. Among authors: tripodo c. Nat Commun. 2020 Jul 14;11(1):3516. doi: 10.1038/s41467-020-17091-x. Nat Commun. 2020. PMID: 32665580 Free PMC article.
Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome.
Capaci V, Bascetta L, Fantuz M, Beznoussenko GV, Sommaggio R, Cancila V, Bisso A, Campaner E, Mironov AA, Wiśniewski JR, Ulloa Severino L, Scaini D, Bossi F, Lees J, Alon N, Brunga L, Malkin D, Piazza S, Collavin L, Rosato A, Bicciato S, Tripodo C, Mantovani F, Del Sal G. Capaci V, et al. Among authors: tripodo c. Nat Commun. 2020 Aug 7;11(1):3945. doi: 10.1038/s41467-020-17596-5. Nat Commun. 2020. PMID: 32770028 Free PMC article.
Intra-tumour heterogeneity of diffuse large B-cell lymphoma involves the induction of diversified stroma-tumour interfaces.
Sangaletti S, Iannelli F, Zanardi F, Cancila V, Portararo P, Botti L, Vacca D, Chiodoni C, Di Napoli A, Valenti C, Rizzello C, Vegliante MC, Pisati F, Gulino A, Ponzoni M, Colombo MP, Tripodo C. Sangaletti S, et al. Among authors: tripodo c. EBioMedicine. 2020 Nov;61:103055. doi: 10.1016/j.ebiom.2020.103055. Epub 2020 Oct 20. EBioMedicine. 2020. PMID: 33096480 Free PMC article.
FUNDING: This study has been supported by the Italian Foundation for Cancer Research (AIRC) (grants 15999 and 22145 to C. Tripodo) and by the University of Palermo....
FUNDING: This study has been supported by the Italian Foundation for Cancer Research (AIRC) (grants 15999 and 22145 to C. Tripodo
T Cells Expressing Receptor Recombination/Revision Machinery Are Detected in the Tumor Microenvironment and Expanded in Genomically Over-unstable Models.
Morello G, Cancila V, La Rosa M, Germano G, Lecis D, Amodio V, Zanardi F, Iannelli F, Greco D, La Paglia L, Fiannaca A, Urso AM, Graziano G, Ferrari F, Pupa SM, Sangaletti S, Chiodoni C, Pruneri G, Bardelli A, Colombo MP, Tripodo C. Morello G, et al. Among authors: tripodo c. Cancer Immunol Res. 2021 Jul;9(7):825-837. doi: 10.1158/2326-6066.CIR-20-0645. Epub 2021 May 3. Cancer Immunol Res. 2021. PMID: 33941587
YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS-STING.
Sladitschek-Martens HL, Guarnieri A, Brumana G, Zanconato F, Battilana G, Xiccato RL, Panciera T, Forcato M, Bicciato S, Guzzardo V, Fassan M, Ulliana L, Gandin A, Tripodo C, Foiani M, Brusatin G, Cordenonsi M, Piccolo S. Sladitschek-Martens HL, et al. Among authors: tripodo c. Nature. 2022 Jul;607(7920):790-798. doi: 10.1038/s41586-022-04924-6. Epub 2022 Jun 29. Nature. 2022. PMID: 35768505 Free PMC article.
Tissue fluidification promotes a cGAS-STING cytosolic DNA response in invasive breast cancer.
Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, Abdo H, Cancila V, Beznoussenko GV, Della Chiara G, Pagani M, Malinverno C, Bhattacharya D, Pisati F, Yu W, Galimberti V, Bonizzi G, Martini E, Mironov AA, Gioia U, Ascione F, Li Q, Havas K, Magni S, Lavagnino Z, Pennacchio FA, Maiuri P, Caponi S, Mattarelli M, Martino S, d'Adda di Fagagna F, Rossi C, Lucioni M, Tancredi R, Pedrazzoli P, Vecchione A, Petrini C, Ferrari F, Lanzuolo C, Bertalot G, Nader G, Foiani M, Piel M, Cerbino R, Giavazzi F, Tripodo C, Scita G. Frittoli E, et al. Among authors: tripodo c. Nat Mater. 2023 May;22(5):644-655. doi: 10.1038/s41563-022-01431-x. Epub 2022 Dec 29. Nat Mater. 2023. PMID: 36581770 Free PMC article.
Author Correction: Tissue fluidification promotes a cGAS-STING cytosolic DNA response in invasive breast cancer.
Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, Abdo H, Cancila V, Beznoussenko GV, Della Chiara G, Pagani M, Malinverno C, Bhattacharya D, Pisati F, Yu W, Galimberti V, Bonizzi G, Martini E, Mironov AA, Gioia U, Ascione F, Li Q, Havas K, Magni S, Lavagnino Z, Pennacchio FA, Maiuri P, Caponi S, Mattarelli M, Martino S, d'Adda di Fagagna F, Rossi C, Lucioni M, Tancredi R, Pedrazzoli P, Vecchione A, Petrini C, Ferrari F, Lanzuolo C, Bertalot G, Nader G, Foiani M, Piel M, Cerbino R, Giavazzi F, Tripodo C, Scita G. Frittoli E, et al. Among authors: tripodo c. Nat Mater. 2023 Mar;22(3):400. doi: 10.1038/s41563-023-01479-3. Nat Mater. 2023. PMID: 36702890 Free PMC article. No abstract available.
305 results