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Page 1
Dietary conjugated linoleic acid links reduced intestinal inflammation to amelioration of CNS autoimmunity.
Fleck AK, Hucke S, Teipel F, Eschborn M, Janoschka C, Liebmann M, Wami H, Korn L, Pickert G, Hartwig M, Wirth T, Herold M, Koch K, Falk-Paulsen M, Dobrindt U, Kovac S, Gross CC, Rosenstiel P, Trautmann M, Wiendl H, Schuppan D, Kuhlmann T, Klotz L. Fleck AK, et al. Among authors: eschborn m. Brain. 2021 May 7;144(4):1152-1166. doi: 10.1093/brain/awab040. Brain. 2021. PMID: 33899089 Free PMC article. Clinical Trial.
Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity.
Liebmann M, Hucke S, Koch K, Eschborn M, Ghelman J, Chasan AI, Glander S, Schädlich M, Kuhlencord M, Daber NM, Eveslage M, Beyer M, Dietrich M, Albrecht P, Stoll M, Busch KB, Wiendl H, Roth J, Kuhlmann T, Klotz L. Liebmann M, et al. Among authors: eschborn m. Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8017-E8026. doi: 10.1073/pnas.1721049115. Epub 2018 Aug 2. Proc Natl Acad Sci U S A. 2018. PMID: 30072431 Free PMC article.
Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.
Klotz L, Eschborn M, Lindner M, Liebmann M, Herold M, Janoschka C, Torres Garrido B, Schulte-Mecklenbeck A, Gross CC, Breuer J, Hundehege P, Posevitz V, Pignolet B, Nebel G, Glander S, Freise N, Austermann J, Wirth T, Campbell GR, Schneider-Hohendorf T, Eveslage M, Brassat D, Schwab N, Loser K, Roth J, Busch KB, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H. Klotz L, et al. Among authors: eschborn m. Sci Transl Med. 2019 May 1;11(490):eaao5563. doi: 10.1126/scitranslmed.aao5563. Sci Transl Med. 2019. PMID: 31043571 Clinical Trial.
Evaluation of Age-Dependent Immune Signatures in Patients With Multiple Sclerosis.
Eschborn M, Pawlitzki M, Wirth T, Nelke C, Pfeuffer S, Schulte-Mecklenbeck A, Lohmann L, Rolfes L, Pape K, Eveslage M, Bittner S, Gross CC, Ruck T, Wiendl H, Meuth SG, Klotz L. Eschborn M, et al. Neurol Neuroimmunol Neuroinflamm. 2021 Oct 19;8(6):e1094. doi: 10.1212/NXI.0000000000001094. Print 2021 Nov. Neurol Neuroimmunol Neuroinflamm. 2021. PMID: 34667129 Free PMC article.
CNS Pericytes Modulate Local T Cell Infiltration in EAE.
Koch K, Lindner M, Fleck AK, Liebmann M, Eschborn M, Zondler L, Diéguez-Hurtado R, Adams RH, Meyer Zu Hörste G, Zarbock A, Kuhlmann T, Wiendl H, Klotz L. Koch K, et al. Among authors: eschborn m. Int J Mol Sci. 2022 Oct 28;23(21):13081. doi: 10.3390/ijms232113081. Int J Mol Sci. 2022. PMID: 36361868 Free PMC article.
Enhanced pathogenicity of Th17 cells due to natalizumab treatment: Implications for MS disease rebound.
Janoschka C, Lindner M, Koppers N, Starost L, Liebmann M, Eschborn M, Schneider-Hohendorf T, Windener F, Schafflick D, Fleck AK, Koch K, Deffner M, Schwarze AS, Schulte-Mecklenbeck A, Metz I, Meuth SG, Gross CC, Meyer Zu Hörste G, Schwab N, Kuhlmann T, Wiendl H, Stoll M, Klotz L. Janoschka C, et al. Among authors: eschborn m. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2209944120. doi: 10.1073/pnas.2209944120. Epub 2022 Dec 27. Proc Natl Acad Sci U S A. 2023. PMID: 36574650 Free PMC article.
Attenuation of immune activation in patients with multiple sclerosis on a wheat-reduced diet: a pilot crossover trial.
Engel S, Klotz L, Wirth T, Fleck AK, Pickert G, Eschborn M, Kreuzburg S, Curella V, Bittner S, Zipp F, Schuppan D, Luessi F. Engel S, et al. Among authors: eschborn m. Ther Adv Neurol Disord. 2023 Jun 25;16:17562864231170928. doi: 10.1177/17562864231170928. eCollection 2023. Ther Adv Neurol Disord. 2023. PMID: 37384112 Free PMC article.
Endurance Exercise Attenuates Established Progressive Experimental Autoimmune Encephalomyelitis and Is Associated with an Amelioration of Innate Immune Responses in NOD Mice.
Schiffmann D, Lampkemeyer V, Lindner M, Fleck AK, Koch K, Eschborn M, Liebmann M, Strecker JK, Minnerup J, Wiendl H, Klotz L. Schiffmann D, et al. Among authors: eschborn m. Int J Mol Sci. 2023 Oct 31;24(21):15798. doi: 10.3390/ijms242115798. Int J Mol Sci. 2023. PMID: 37958787 Free PMC article.
12 results