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Page 1
Drugging histone methyltransferases in cancer.
Richart L, Margueron R. Richart L, et al. Among authors: margueron r. Curr Opin Chem Biol. 2020 Jun;56:51-62. doi: 10.1016/j.cbpa.2019.11.009. Epub 2020 Jan 23. Curr Opin Chem Biol. 2020. PMID: 31981999 Review.
XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation.
Richart L, Picod-Chedotel ML, Wassef M, Macario M, Aflaki S, Salvador MA, Héry T, Dauphin A, Wicinski J, Chevrier V, Pastor S, Guittard G, Le Cam S, Kamhawi H, Castellano R, Guasch G, Charafe-Jauffret E, Heard E, Margueron R, Ginestier C. Richart L, et al. Among authors: margueron r. Cell. 2022 Jun 9;185(12):2164-2183.e25. doi: 10.1016/j.cell.2022.04.034. Epub 2022 May 20. Cell. 2022. PMID: 35597241 Free article.
EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition.
Romero P, Richart L, Aflaki S, Petitalot A, Burton M, Michaud A, Masliah-Planchon J, Kuhnowski F, Le Cam S, Baliñas-Gavira C, Méaudre C, Luscan A, Hamza A, Legoix P, Vincent-Salomon A, Wassef M, Holoch D, Margueron R. Romero P, et al. Among authors: margueron r. Nat Commun. 2024 Apr 24;15(1):3452. doi: 10.1038/s41467-024-47701-x. Nat Commun. 2024. PMID: 38658543 Free PMC article.
Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.
Sanulli S, Justin N, Teissandier A, Ancelin K, Portoso M, Caron M, Michaud A, Lombard B, da Rocha ST, Offer J, Loew D, Servant N, Wassef M, Burlina F, Gamblin SJ, Heard E, Margueron R. Sanulli S, et al. Among authors: margueron r. Mol Cell. 2015 Mar 5;57(5):769-783. doi: 10.1016/j.molcel.2014.12.020. Epub 2015 Jan 22. Mol Cell. 2015. PMID: 25620564 Free PMC article.
The Multiple Facets of PRC2 Alterations in Cancers.
Wassef M, Margueron R. Wassef M, et al. Among authors: margueron r. J Mol Biol. 2017 Jun 30;429(13):1978-1993. doi: 10.1016/j.jmb.2016.10.012. Epub 2016 Oct 12. J Mol Biol. 2017. PMID: 27742591 Review.
PRC2 is dispensable for HOTAIR-mediated transcriptional repression.
Portoso M, Ragazzini R, Brenčič Ž, Moiani A, Michaud A, Vassilev I, Wassef M, Servant N, Sargueil B, Margueron R. Portoso M, et al. Among authors: margueron r. EMBO J. 2017 Apr 13;36(8):981-994. doi: 10.15252/embj.201695335. Epub 2017 Feb 6. EMBO J. 2017. PMID: 28167697 Free PMC article.
BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation.
Campagne A, Lee MK, Zielinski D, Michaud A, Le Corre S, Dingli F, Chen H, Shahidian LZ, Vassilev I, Servant N, Loew D, Pasmant E, Postel-Vinay S, Wassef M, Margueron R. Campagne A, et al. Among authors: margueron r. Nat Commun. 2019 Jan 21;10(1):348. doi: 10.1038/s41467-018-08255-x. Nat Commun. 2019. PMID: 30664650 Free PMC article.
76 results