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Symptomatic and preventive effects of the novel phosphodiesterase-9 inhibitor BI 409306 in an immune-mediated model of neurodevelopmental disorders.
Scarborough J, Mattei D, Dorner-Ciossek C, Sand M, Arban R, Rosenbrock H, Richetto J, Meyer U. Scarborough J, et al. Among authors: rosenbrock h. Neuropsychopharmacology. 2021 Jul;46(8):1526-1534. doi: 10.1038/s41386-021-01016-3. Epub 2021 May 3. Neuropsychopharmacology. 2021. PMID: 33941860 Free PMC article.
Role of PDE9 in Cognition.
Dorner-Ciossek C, Kroker KS, Rosenbrock H. Dorner-Ciossek C, et al. Among authors: rosenbrock h. Adv Neurobiol. 2017;17:231-254. doi: 10.1007/978-3-319-58811-7_9. Adv Neurobiol. 2017. PMID: 28956335 Review.
The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers.
Moschetti V, Kim M, Sand M, Wunderlich G, Andersen G, Feifel U, Jang IJ, Timmer W, Rosenbrock H, Boland K. Moschetti V, et al. Among authors: rosenbrock h. Eur Neuropsychopharmacol. 2018 May;28(5):643-655. doi: 10.1016/j.euroneuro.2018.01.003. Epub 2018 Mar 19. Eur Neuropsychopharmacol. 2018. PMID: 29567399 Free article. Clinical Trial.
Evaluation of Pharmacokinetics and Pharmacodynamics of BI 425809, a Novel GlyT1 Inhibitor: Translational Studies.
Rosenbrock H, Desch M, Kleiner O, Dorner-Ciossek C, Schmid B, Keller S, Schlecker C, Moschetti V, Goetz S, Liesenfeld KH, Fillon G, Giovannini R, Ramael S, Wunderlich G, Wind S. Rosenbrock H, et al. Clin Transl Sci. 2018 Nov;11(6):616-623. doi: 10.1111/cts.12578. Epub 2018 Aug 23. Clin Transl Sci. 2018. PMID: 30136756 Free PMC article. Clinical Trial.
55 results