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Early initiation of hydroxyurea (hydroxycarbamide) using individualised, pharmacokinetics-guided dosing can produce sustained and nearly pancellular expression of fetal haemoglobin in children with sickle cell anaemia.
Quinn CT, Niss O, Dong M, Pfeiffer A, Korpik J, Reynaud M, Bonar H, Kalfa TA, Smart LR, Malik P, Ware RE, Vinks AA, McGann PT. Quinn CT, et al. Among authors: korpik j. Br J Haematol. 2021 Aug;194(3):617-625. doi: 10.1111/bjh.17663. Epub 2021 Jul 5. Br J Haematol. 2021. PMID: 34227124 Free PMC article. Clinical Trial.
Automated Oxygen Gradient Ektacytometry: A Novel Biomarker in Sickle Cell Anemia.
Sadaf A, Seu KG, Thaman E, Fessler R, Konstantinidis DG, Bonar HA, Korpik J, Ware RE, McGann PT, Quinn CT, Kalfa TA. Sadaf A, et al. Among authors: korpik j. Front Physiol. 2021 Mar 25;12:636609. doi: 10.3389/fphys.2021.636609. eCollection 2021. Front Physiol. 2021. PMID: 33841173 Free PMC article.