Eissa IH - Search Results

1

Discovery of thieno[2,3-d]pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents.

El-Metwally SA, Abou-El-Regal MM, Eissa IH, Mehany ABM, Mahdy HA, Elkady H, Elwan A, Elkaeed EB. El-Metwally SA, et al. Among authors: eissa ih. Bioorg Chem. 2021 Jul;112:104947. doi: 10.1016/j.bioorg.2021.104947. Epub 2021 Apr 27. Bioorg Chem. 2021. PMID: 33964580

2

Design, synthesis, molecular modeling and biological evaluation of novel 1H-pyrazolo[3,4-b]pyridine derivatives as potential anticancer agents.

Eissa IH, El-Naggar AM, El-Hashash MA. Eissa IH, et al. Bioorg Chem. 2016 Aug;67:43-56. doi: 10.1016/j.bioorg.2016.05.006. Epub 2016 May 20. Bioorg Chem. 2016. PMID: 27253830

3

Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of novel quinoxaline derivatives as potential PPARγ and SUR agonists.

Ibrahim MK, Eissa IH, Abdallah AE, Metwaly AM, Radwan MM, ElSohly MA. Ibrahim MK, et al. Among authors: eissa ih. Bioorg Med Chem. 2017 Feb 15;25(4):1496-1513. doi: 10.1016/j.bmc.2017.01.015. Epub 2017 Jan 16. Bioorg Med Chem. 2017. PMID: 28117121

4

Design and Discovery of Novel Quinoxaline Derivatives as Dual DNA Intercalators and Topoisomerase II Inhibitors.

Eissa IH, El-Naggar AM, El-Sattar NEAA, Youssef ASA. Eissa IH, et al. Anticancer Agents Med Chem. 2018;18(2):195-209. doi: 10.2174/1871520617666170710182405. Anticancer Agents Med Chem. 2018. PMID: 28699490

5

Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of quinazolin-4(3H)-one derivatives as potential PPARγ and SUR agonists.

Ibrahim MK, Eissa IH, Alesawy MS, Metwaly AM, Radwan MM, ElSohly MA. Ibrahim MK, et al. Among authors: eissa ih. Bioorg Med Chem. 2017 Sep 1;25(17):4723-4744. doi: 10.1016/j.bmc.2017.07.015. Epub 2017 Jul 8. Bioorg Med Chem. 2017. PMID: 28720328

6

Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies.

Eldehna WM, Abo-Ashour MF, Nocentini A, Gratteri P, Eissa IH, Fares M, Ismael OE, Ghabbour HA, Elaasser MM, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Among authors: eissa ih. Eur J Med Chem. 2017 Oct 20;139:250-262. doi: 10.1016/j.ejmech.2017.07.073. Epub 2017 Aug 1. Eur J Med Chem. 2017. PMID: 28802125

7

Synthesis, characterization and molecular docking studies of thiouracil derivatives as potent thymidylate synthase inhibitors and potential anticancer agents.

El-Naggar AM, Abou-El-Regal MM, El-Metwally SA, Sherbiny FF, Eissa IH. El-Naggar AM, et al. Among authors: eissa ih. Mol Divers. 2017 Nov;21(4):967-983. doi: 10.1007/s11030-017-9776-1. Epub 2017 Aug 16. Mol Divers. 2017. PMID: 28815411

8

Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors.

Ibrahim MK, Taghour MS, Metwaly AM, Belal A, Mehany ABM, Elhendawy MA, Radwan MM, Yassin AM, El-Deeb NM, Hafez EE, ElSohly MA, Eissa IH. Ibrahim MK, et al. Among authors: eissa ih. Eur J Med Chem. 2018 Jul 15;155:117-134. doi: 10.1016/j.ejmech.2018.06.004. Epub 2018 Jun 4. Eur J Med Chem. 2018. PMID: 29885574

9

Design, synthesis and anticancer evaluation of 1H-pyrazolo[3,4-d]pyrimidine derivatives as potent EGFR^WT and EGFR^T790M inhibitors and apoptosis inducers.

Gaber AA, Bayoumi AH, El-Morsy AM, Sherbiny FF, Mehany ABM, Eissa IH. Gaber AA, et al. Among authors: eissa ih. Bioorg Chem. 2018 Oct;80:375-395. doi: 10.1016/j.bioorg.2018.06.017. Epub 2018 Jun 12. Bioorg Chem. 2018. PMID: 29986185

10

Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers.

Elmetwally SA, Saied KF, Eissa IH, Elkaeed EB. Elmetwally SA, et al. Among authors: eissa ih. Bioorg Chem. 2019 Jul;88:102944. doi: 10.1016/j.bioorg.2019.102944. Epub 2019 Apr 25. Bioorg Chem. 2019. PMID: 31051400

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