Laufer SA - Search Results

1

Design and Synthesis of Highly Selective Brain Penetrant p38α Mitogen-Activated Protein Kinase Inhibitors.

Tormählen NM, Martorelli M, Kuhn A, Maier F, Guezguez J, Burnet M, Albrecht W, Laufer SA, Koch P. Tormählen NM, et al. Among authors: laufer sa. J Med Chem. 2022 Jan 27;65(2):1225-1242. doi: 10.1021/acs.jmedchem.0c01773. Epub 2021 May 11. J Med Chem. 2022. PMID: 33974419

2

From imidazoles to pyrimidines: new inhibitors of cytokine release.

Laufer SA, Wagner GK. Laufer SA, et al. J Med Chem. 2002 Jun 20;45(13):2733-40. doi: 10.1021/jm011098a. J Med Chem. 2002. PMID: 12061876

3

Imidazole inhibitors of cytokine release: probing substituents in the 2 position.

Laufer SA, Striegel HG, Wagner GK. Laufer SA, et al. J Med Chem. 2002 Oct 10;45(21):4695-705. doi: 10.1021/jm020873z. J Med Chem. 2002. PMID: 12361396

4

An in-vitro screening assay for the detection of inhibitors of proinflammatory cytokine synthesis: a useful tool for the development of new antiarthritic and disease modifying drugs.

Laufer S, Greim C, Bertsche T. Laufer S, et al. Osteoarthritis Cartilage. 2002 Dec;10(12):961-7. doi: 10.1053/joca.2002.0851. Osteoarthritis Cartilage. 2002. PMID: 12464556 Free article.

5

Identification of regioisomers in a series of N-substituted pyridin-4-yl imidazole derivatives by regiospecific synthesis, GC/MS, and 1H NMR.

Wagner GK, Kotschenreuther D, Zimmermann W, Laufer SA. Wagner GK, et al. Among authors: laufer sa. J Org Chem. 2003 May 30;68(11):4527-30. doi: 10.1021/jo026619w. J Org Chem. 2003. PMID: 12762762

6

Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes.

Laufer SA, Wagner GK, Kotschenreuther DA, Albrecht W. Laufer SA, et al. J Med Chem. 2003 Jul 17;46(15):3230-44. doi: 10.1021/jm030766k. J Med Chem. 2003. PMID: 12852754

7

Tetrasubstituted imidazole inhibitors of cytokine release: probing substituents in the N-1 position.

Laufer SA, Zimmermann W, Ruff KJ. Laufer SA, et al. J Med Chem. 2004 Dec 2;47(25):6311-25. doi: 10.1021/jm0496584. J Med Chem. 2004. PMID: 15566301

8

Synthesis and biological testing of purine derivatives as potential ATP-competitive kinase inhibitors.

Laufer SA, Domeyer DM, Scior TR, Albrecht W, Hauser DR. Laufer SA, et al. J Med Chem. 2005 Feb 10;48(3):710-22. doi: 10.1021/jm0408767. J Med Chem. 2005. PMID: 15689155

9

New approaches to the treatment of inflammatory disorders small molecule inhibitors of p38 MAP kinase.

Peifer C, Wagner G, Laufer S. Peifer C, et al. Curr Top Med Chem. 2006;6(2):113-49. doi: 10.2174/156802606775270323. Curr Top Med Chem. 2006. PMID: 16454763 Review.

10

Substituted isoxazoles as potent inhibitors of p38 MAP kinase.

Laufer SA, Margutti S, Fritz MD. Laufer SA, et al. ChemMedChem. 2006 Feb;1(2):197-207. doi: 10.1002/cmdc.200500025. ChemMedChem. 2006. PMID: 16892352

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

414 results

Search Page

Filters