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Methylation of the androgen receptor minimal promoter silences transcription in human prostate cancer.
Kinoshita H, Shi Y, Sandefur C, Meisner LF, Chang C, Choon A, Reznikoff CR, Bova GS, Friedl A, Jarrard DF. Kinoshita H, et al. Among authors: jarrard df. Cancer Res. 2000 Jul 1;60(13):3623-30. Cancer Res. 2000. PMID: 10910077
The transcriptional block underlying this phenomenon is not known, but we have proposed that methylation of CpG sites in the AR promoter may reversibly inactivate transcription of the AR (D. F. Jarrard et al, Cancer Res., 58: 5310-5314, 1998). In this study, detaile …
The transcriptional block underlying this phenomenon is not known, but we have proposed that methylation of CpG sites in the AR promoter may …
179 results